2ji5

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[[Image:2ji5.gif|left|200px]]
 
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==Structure of UMP kinase from Pyrococcus furiosus complexed with UTP==
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The line below this paragraph, containing "STRUCTURE_2ji5", creates the "Structure Box" on the page.
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<StructureSection load='2ji5' size='340' side='right'caption='[[2ji5]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2ji5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JI5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JI5 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UTP:URIDINE+5-TRIPHOSPHATE'>UTP</scene></td></tr>
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{{STRUCTURE_2ji5| PDB=2ji5 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ji5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ji5 OCA], [https://pdbe.org/2ji5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ji5 RCSB], [https://www.ebi.ac.uk/pdbsum/2ji5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ji5 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PYRH_PYRFU PYRH_PYRFU] Catalyzes the reversible phosphorylation of UMP to UDP, with ATP as the most efficient phosphate donor.<ref>PMID:15698963</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ji/2ji5_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ji5 ConSurf].
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<div style="clear:both"></div>
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'''STRUCTURE OF UMP KINASE FROM PYROCOCCUS FURIOSUS COMPLEXED WITH UTP'''
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==See Also==
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*[[Uridylate kinase|Uridylate kinase]]
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== References ==
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==About this Structure==
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<references/>
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2JI5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JI5 OCA].
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
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[[Category: Single protein]]
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[[Category: Marco-Marin C]]
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[[Category: Marco-Marin, C.]]
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[[Category: Rubio V]]
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[[Category: Rubio, V.]]
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[[Category: Allosteric regulation]]
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[[Category: Amino acid kinase]]
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[[Category: Kinase]]
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[[Category: Phosphotranspherase]]
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[[Category: Pyrimidine biosynthesis]]
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[[Category: Pyrimidine metabolism]]
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[[Category: Transferase]]
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[[Category: Ump kinase]]
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[[Category: Uridylate kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 08:57:00 2008''
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Current revision

Structure of UMP kinase from Pyrococcus furiosus complexed with UTP

PDB ID 2ji5

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