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2k1g

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[[Image:2k1g.jpg|left|200px]]
 
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==Solution NMR structure of lipoprotein spr from Escherichia coli K12. Northeast Structural Genomics target ER541-37-162==
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The line below this paragraph, containing "STRUCTURE_2k1g", creates the "Structure Box" on the page.
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<StructureSection load='2k1g' size='340' side='right'caption='[[2k1g]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2k1g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2jyx 2jyx]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K1G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K1G FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k1g OCA], [https://pdbe.org/2k1g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k1g RCSB], [https://www.ebi.ac.uk/pdbsum/2k1g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k1g ProSAT], [https://www.topsan.org/Proteins/NESGC/2k1g TOPSAN]</span></td></tr>
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{{STRUCTURE_2k1g| PDB=2k1g | SCENE= }}
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</table>
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== Function ==
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'''Solution NMR structure of lipoprotein spr from Escherichia coli K12. Northeast Structural Genomics target ER541-37-162'''
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[https://www.uniprot.org/uniprot/MEPS_ECOLI MEPS_ECOLI] A murein DD-endopeptidase with specificity for D-Ala-meso-diaminopimelic acid (mDAP) cross-links. Its role is probably to cleave D-Ala-mDAP cross-links to allow insertion of new glycans and thus cell wall expansion. Functionally redundant with MepM and MepH. Also has weak LD-carboxypeptidase activity on L-mDAP-D-Ala peptide bonds. Partially suppresses a prc disruption mutant.<ref>PMID:23062283</ref> <ref>PMID:9158724</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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2K1G is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k12 Escherichia coli k12]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2jyx 2jyx]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K1G OCA].
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<jmolCheckbox>
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[[Category: Escherichia coli k12]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k1/2k1g_consurf.spt"</scriptWhenChecked>
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[[Category: Single protein]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Acton, T B.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Aramini, J M.]]
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</jmolCheckbox>
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[[Category: Baran, M C.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k1g ConSurf].
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[[Category: Huang, Y J.]]
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<div style="clear:both"></div>
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[[Category: Jiang, M.]]
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== References ==
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[[Category: Liu, J.]]
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<references/>
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[[Category: Maglaqui, M.]]
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__TOC__
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[[Category: Montelione, G T.]]
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</StructureSection>
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Escherichia coli K-12]]
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[[Category: Rossi, P.]]
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[[Category: Large Structures]]
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[[Category: Rost, B.]]
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[[Category: Acton TB]]
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[[Category: Swapna, G V.T.]]
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[[Category: Aramini JM]]
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[[Category: Xiao, R.]]
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[[Category: Baran MC]]
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[[Category: Zhao, L.]]
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[[Category: Huang YJ]]
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[[Category: Bacterial lipoprotein]]
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[[Category: Jiang M]]
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[[Category: Construct optimized]]
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[[Category: Liu J]]
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[[Category: Cysteine peptidase]]
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[[Category: Maglaqui M]]
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[[Category: Membrane]]
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[[Category: Montelione GT]]
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[[Category: Nesg]]
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[[Category: Rossi P]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: Rost B]]
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[[Category: Nplc/p60 family]]
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[[Category: Swapna GVT]]
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[[Category: Palmitate]]
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[[Category: Xiao R]]
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[[Category: Protein structure initiative]]
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[[Category: Zhao L]]
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[[Category: Psi-2]]
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[[Category: Solution nmr structure]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 09:27:57 2008''
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Current revision

Solution NMR structure of lipoprotein spr from Escherichia coli K12. Northeast Structural Genomics target ER541-37-162

PDB ID 2k1g

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