2o86

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[[Image:2o86.gif|left|200px]]
 
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==Crystal structure of a ternary complex of buffalo lactoperoxidase with nitrate and iodide at 2.8 A resolution==
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The line below this paragraph, containing "STRUCTURE_2o86", creates the "Structure Box" on the page.
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<StructureSection load='2o86' size='340' side='right'caption='[[2o86]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2o86]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bubalus_bubalis Bubalus bubalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O86 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O86 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
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{{STRUCTURE_2o86| PDB=2o86 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o86 OCA], [https://pdbe.org/2o86 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o86 RCSB], [https://www.ebi.ac.uk/pdbsum/2o86 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o86 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PERL_BUBBU PERL_BUBBU] Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN). May protect the udder from infection and promote growth in newborn calves. Inhibits growth of the following bacterial species: E.coli, K.pneumoniae, P.aeruginosa, S.sonnei, S.saphrophyticus, S.epidermidis, and S.dysenteriae.<ref>PMID:12071645</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o8/2o86_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2o86 ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of a ternary complex of buffalo lactoperoxidase with nitrate and iodide at 2.8 A resolution'''
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==See Also==
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*[[Lactoperoxidase|Lactoperoxidase]]
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== References ==
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==About this Structure==
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<references/>
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O86 OCA].
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__TOC__
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[[Category: Peroxidase]]
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</StructureSection>
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[[Category: Kaur, P.]]
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[[Category: Bubalus bubalis]]
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[[Category: Sharma, S.]]
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[[Category: Large Structures]]
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[[Category: Sheikh, I A.]]
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[[Category: Kaur P]]
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[[Category: Singh, A K.]]
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[[Category: Sharma S]]
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[[Category: Singh, N.]]
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[[Category: Sheikh IA]]
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[[Category: Singh, T P.]]
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[[Category: Singh AK]]
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[[Category: Anion]]
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[[Category: Singh N]]
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[[Category: Heme]]
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[[Category: Singh TP]]
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[[Category: Peroxidase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 10:26:28 2008''
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Current revision

Crystal structure of a ternary complex of buffalo lactoperoxidase with nitrate and iodide at 2.8 A resolution

PDB ID 2o86

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