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2oqk
From Proteopedia
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| - | [[Image:2oqk.gif|left|200px]] | ||
| - | + | ==Crystal structure of putative Cryptosporidium parvum translation initiation factor eIF-1A== | |
| - | + | <StructureSection load='2oqk' size='340' side='right'caption='[[2oqk]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2oqk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OQK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OQK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oqk OCA], [https://pdbe.org/2oqk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oqk RCSB], [https://www.ebi.ac.uk/pdbsum/2oqk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oqk ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/Q5CVP1_CRYPI Q5CVP1_CRYPI] Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.[RuleBase:RU004365] | |
| - | + | == Evolutionary Conservation == | |
| - | == | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| - | [[ | + | <jmolCheckbox> |
| - | [[ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oq/2oqk_consurf.spt"</scriptWhenChecked> |
| - | [[ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [ | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [ | + | </jmolCheckbox> |
| - | [[ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2oqk ConSurf]. |
| - | [ | + | <div style="clear:both"></div> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Cryptosporidium parvum Iowa II]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Altamentova S]] |
| - | [[Category: | + | [[Category: Arrowsmith CH]] |
| - | [[Category: | + | [[Category: Bochkarev A]] |
| - | [[Category: | + | [[Category: Brokx SJ]] |
| - | [[Category: | + | [[Category: Dong A]] |
| - | [[Category: | + | [[Category: Edwards AM]] |
| - | [[Category: | + | [[Category: Hassanali A]] |
| - | [[Category: | + | [[Category: Hui R]] |
| - | [[Category: | + | [[Category: Kozieradzki I]] |
| - | [[Category: | + | [[Category: Lew J]] |
| - | [[Category: | + | [[Category: Lin L]] |
| - | [[Category: | + | [[Category: Qiu W]] |
| - | [[Category: | + | [[Category: Sundstrom M]] |
| - | [[Category: | + | [[Category: Vedadi M]] |
| - | + | [[Category: Wasney G]] | |
| + | [[Category: Weigelt J]] | ||
| + | [[Category: Zhao Y]] | ||
Current revision
Crystal structure of putative Cryptosporidium parvum translation initiation factor eIF-1A
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Categories: Cryptosporidium parvum Iowa II | Large Structures | Altamentova S | Arrowsmith CH | Bochkarev A | Brokx SJ | Dong A | Edwards AM | Hassanali A | Hui R | Kozieradzki I | Lew J | Lin L | Qiu W | Sundstrom M | Vedadi M | Wasney G | Weigelt J | Zhao Y

