2p3s

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[[Image:2p3s.jpg|left|200px]]
 
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==Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (G214R/Q199R)==
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The line below this paragraph, containing "STRUCTURE_2p3s", creates the "Structure Box" on the page.
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<StructureSection load='2p3s' size='340' side='right'caption='[[2p3s]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2p3s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P3S FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AP5:BIS(ADENOSINE)-5-PENTAPHOSPHATE'>AP5</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_2p3s| PDB=2p3s | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3s OCA], [https://pdbe.org/2p3s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p3s RCSB], [https://www.ebi.ac.uk/pdbsum/2p3s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p3s ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KAD_BACSU KAD_BACSU] Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. This small ubiquitous enzyme involved in the energy metabolism and nucleotide synthesis, is essential for maintenance and cell growth.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p3/2p3s_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p3s ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (G214R/Q199R)'''
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==See Also==
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*[[Adenylate kinase 3D structures|Adenylate kinase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2P3S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3S OCA].
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[[Category: Adenylate kinase]]
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[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Counago, R.]]
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[[Category: Counago R]]
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[[Category: Myers, J.]]
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[[Category: Myers J]]
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[[Category: Shamoo, Y.]]
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[[Category: Shamoo Y]]
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[[Category: Wilson, C J.]]
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[[Category: Wilson CJ]]
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[[Category: Wu, G.]]
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[[Category: Wu G]]
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[[Category: Adenylate kinase]]
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[[Category: Directed evolution]]
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[[Category: Experimental adaptive evolution]]
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[[Category: Thermostability]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 12:17:13 2008''
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Current revision

Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (G214R/Q199R)

PDB ID 2p3s

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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