2por

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[[Image:2por.gif|left|200px]]
 
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==STRUCTURE OF PORIN REFINED AT 1.8 ANGSTROMS RESOLUTION==
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The line below this paragraph, containing "STRUCTURE_2por", creates the "Structure Box" on the page.
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<StructureSection load='2por' size='340' side='right'caption='[[2por]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2por]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodobacter_capsulatus Rhodobacter capsulatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2POR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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{{STRUCTURE_2por| PDB=2por | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2por FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2por OCA], [https://pdbe.org/2por PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2por RCSB], [https://www.ebi.ac.uk/pdbsum/2por PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2por ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PORI_RHOCA PORI_RHOCA] Forms channels that allow the passive diffusion of small hydrophilic solutes up to an exclusion limit of about 0.6 kDa.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/po/2por_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2por ConSurf].
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<div style="clear:both"></div>
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'''STRUCTURE OF PORIN REFINED AT 1.8 ANGSTROMS RESOLUTION'''
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==See Also==
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*[[Porin 3D structures|Porin 3D structures]]
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__TOC__
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==Overview==
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</StructureSection>
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The crystal structure of porin from Rhodobacter capsulatus has been refined using the simulated annealing method. The final model consists of all 301 amino acid residues well obeying standard geometry, three calcium ions, 274 solvent molecules, three detergent molecules and one unknown ligand modeled as a detergent molecule. The final crystallographic R-factor is 18.6% based on 42,851 independent reflections in the resolution range 10 to 1.8 A. The model is described in detail.
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[[Category: Large Structures]]
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==About this Structure==
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2POR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rhodobacter_capsulatus Rhodobacter capsulatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POR OCA].
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==Reference==
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Structure of porin refined at 1.8 A resolution., Weiss MS, Schulz GE, J Mol Biol. 1992 Sep 20;227(2):493-509. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1328651 1328651]
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[[Category: Rhodobacter capsulatus]]
[[Category: Rhodobacter capsulatus]]
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[[Category: Single protein]]
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[[Category: Schulz GE]]
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[[Category: Schulz, G E.]]
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[[Category: Weiss MS]]
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[[Category: Weiss, M S.]]
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[[Category: Integral membrane protein porin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 13:33:21 2008''
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Current revision

STRUCTURE OF PORIN REFINED AT 1.8 ANGSTROMS RESOLUTION

PDB ID 2por

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