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1t2q
From Proteopedia
(Difference between revisions)
(New page: 200px<br /> <applet load="1t2q" size="450" color="white" frame="true" align="right" spinBox="true" caption="1t2q, resolution 1.83Å" /> '''The Crystal Structu...) |
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| - | [[Image:1t2q.gif|left|200px]]<br /> | ||
| - | <applet load="1t2q" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1t2q, resolution 1.83Å" /> | ||
| - | '''The Crystal Structure of an NNA7 Fab that recognizes an N-type blood group antigen'''<br /> | ||
| - | == | + | ==The Crystal Structure of an NNA7 Fab that recognizes an N-type blood group antigen== |
| - | + | <StructureSection load='1t2q' size='340' side='right'caption='[[1t2q]], [[Resolution|resolution]] 1.83Å' scene=''> | |
| - | [[ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[1t2q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T2Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T2Q FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.83Å</td></tr> |
| - | [ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr> |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t2q OCA], [https://pdbe.org/1t2q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t2q RCSB], [https://www.ebi.ac.uk/pdbsum/1t2q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t2q ProSAT]</span></td></tr> |
| - | + | </table> | |
| - | [ | + | == Function == |
| - | [[ | + | [https://www.uniprot.org/uniprot/A2NHM3_MOUSE A2NHM3_MOUSE] |
| - | [ | + | == Evolutionary Conservation == |
| - | [[ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [ | + | Check<jmol> |
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t2/1t2q_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t2q ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| + | *[[Antibody 3D structures|Antibody 3D structures]] | ||
| + | *[[Sandbox 20009|Sandbox 20009]] | ||
| + | *[[3D structures of non-human antibody|3D structures of non-human antibody]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Song SC]] | ||
| + | [[Category: Spitalnik SL]] | ||
| + | [[Category: Wedekind JE]] | ||
| + | [[Category: Xie K]] | ||
Current revision
The Crystal Structure of an NNA7 Fab that recognizes an N-type blood group antigen
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