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2yu0
From Proteopedia
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| - | [[Image:2yu0.jpg|left|200px]] | ||
| - | < | + | ==Solution structures of the PAAD_DAPIN domain of mus musculus interferon-activatable protein 205== |
| - | + | <StructureSection load='2yu0' size='340' side='right'caption='[[2yu0]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2yu0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YU0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YU0 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yu0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yu0 OCA], [https://pdbe.org/2yu0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yu0 RCSB], [https://www.ebi.ac.uk/pdbsum/2yu0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yu0 ProSAT], [https://www.topsan.org/Proteins/RSGI/2yu0 TOPSAN]</span></td></tr> | |
| - | + | </table> | |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IFI5B_MOUSE IFI5B_MOUSE] May act as a transcriptional regulator in the myeloid lineage. Inhibits cell growth via p53/TP53 and RB1-dependent and independent pathways.<ref>PMID:15342947</ref> <ref>PMID:16458891</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yu/2yu0_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yu0 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| - | + | *[[Pyrin domain|Pyrin domain]] | |
| - | + | == References == | |
| - | == | + | <references/> |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | + | [[Category: Harada T]] | |
| - | [[Category: Harada | + | [[Category: Kigawa T]] |
| - | [[Category: Kigawa | + | [[Category: Koshiba S]] |
| - | [[Category: Koshiba | + | [[Category: Sato M]] |
| - | + | [[Category: Tochio N]] | |
| - | [[Category: Sato | + | [[Category: Watanabe M]] |
| - | [[Category: Tochio | + | [[Category: Yokoyama S]] |
| - | [[Category: Watanabe | + | |
| - | [[Category: Yokoyama | + | |
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Current revision
Solution structures of the PAAD_DAPIN domain of mus musculus interferon-activatable protein 205
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Categories: Large Structures | Mus musculus | Harada T | Kigawa T | Koshiba S | Sato M | Tochio N | Watanabe M | Yokoyama S

