361d

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[[Image:361d.gif|left|200px]]
 
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==CRYSTAL STRUCTURE OF DOMAIN E OF THERMUS FLAVUS 5S RRNA: A HELICAL RNA-STRUCTURE INCLUDING A TETRALOOP==
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The line below this paragraph, containing "STRUCTURE_361d", creates the "Structure Box" on the page.
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<StructureSection load='361d' size='340' side='right'caption='[[361d]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[361d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=361D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=361D FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=361d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=361d OCA], [https://pdbe.org/361d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=361d RCSB], [https://www.ebi.ac.uk/pdbsum/361d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=361d ProSAT]</span></td></tr>
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{{STRUCTURE_361d| PDB=361d | SCENE= }}
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</table>
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__TOC__
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'''CRYSTAL STRUCTURE OF DOMAIN E OF THERMUS FLAVUS 5S RRNA: A HELICAL RNA-STRUCTURE INCLUDING A TETRALOOP'''
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Betzel C]]
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==Overview==
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[[Category: Erdmann VA]]
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The synthetic RNA fragment 5'-CUGGGCGG(GCGA)CCGCCUGG (nucleotides in parentheses indicate the loop region) corresponds to the natural sequence of domain E from nucleotides 79-97 of the Thermus flavus 5S rRNA including a hairpin loop. The RNA structure determined at 3.0 A and refined to an R-value of 24.1% also represents the first X-ray structure GNRA tetraloop. The loop is in distinctly different conformation from other GNRA tetraloops analyzed by NMR. The conformation of the two molecules in the asymmetric unit is influenced and stabilized by specific intermolecular contacts. The structural features presented here give evidence for the ability of RNA molecules to adapt to specific environments.
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[[Category: Lorenz S]]
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[[Category: Nolte A]]
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==About this Structure==
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[[Category: Perbandt M]]
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=361D OCA].
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==Reference==
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Crystal structure of domain E of Thermus flavus 5S rRNA: a helical RNA structure including a hairpin loop., Perbandt M, Nolte A, Lorenz S, Bald R, Betzel C, Erdmann VA, FEBS Lett. 1998 Jun 12;429(2):211-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9650592 9650592]
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[[Category: Betzel, C.]]
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[[Category: Erdmann, V A.]]
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[[Category: Lorenz, S.]]
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[[Category: Nolte, A.]]
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[[Category: Perbandt, M.]]
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[[Category: Hairpin]]
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[[Category: Mismatched]]
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[[Category: Rna]]
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[[Category: Single strand]]
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[[Category: Tetraloop]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 20:17:18 2008''
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CRYSTAL STRUCTURE OF DOMAIN E OF THERMUS FLAVUS 5S RRNA: A HELICAL RNA-STRUCTURE INCLUDING A TETRALOOP

PDB ID 361d

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