1aqq

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /><applet load="1aqq" size="450" color="white" frame="true" align="right" spinBox="true" caption="1aqq" /> '''AG-SUBSTITUTED METALLOTHIONEIN FROM SACCHARO...)
Current revision (11:33, 22 November 2023) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1aqq.jpg|left|200px]]<br /><applet load="1aqq" size="450" color="white" frame="true" align="right" spinBox="true"
 
-
caption="1aqq" />
 
-
'''AG-SUBSTITUTED METALLOTHIONEIN FROM SACCHAROMYCES CEREVISIAE, NMR, 10 STRUCTURES'''<br />
 
-
==Overview==
+
==AG-SUBSTITUTED METALLOTHIONEIN FROM SACCHAROMYCES CEREVISIAE, NMR, 10 STRUCTURES==
-
3D solution structural calculations for yeast silver(I)-substituted, metallothionein (MT) and native copper(I) MT were completed using, experimentally determined NOE and dihedral angle constraints, in, conjunction with experimentally derived metal-to-Cys connectivities for, AgMT which were assumed identical for CuMT. For the first 40 residues in, both structures, the polypeptide backbone wraps around the metal cluster, in two large parallel loops separated by a deep cleft containing the metal, cluster. Minor differences between the two structures include differences, in hydrogen bonds and the orientation of the N-terminus with the overall, protein volume conserved to within 6.5%.
+
<StructureSection load='1aqq' size='340' side='right'caption='[[1aqq]]' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[1aqq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AQQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AQQ FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AG:SILVER+ION'>AG</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1aqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1aqq OCA], [https://pdbe.org/1aqq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1aqq RCSB], [https://www.ebi.ac.uk/pdbsum/1aqq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1aqq ProSAT]</span></td></tr>
 +
</table>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
3D solution structural calculations for yeast silver(I)-substituted metallothionein (MT) and native copper(I) MT were completed using experimentally determined NOE and dihedral angle constraints, in conjunction with experimentally derived metal-to-Cys connectivities for AgMT which were assumed identical for CuMT. For the first 40 residues in both structures, the polypeptide backbone wraps around the metal cluster in two large parallel loops separated by a deep cleft containing the metal cluster. Minor differences between the two structures include differences in hydrogen bonds and the orientation of the N-terminus with the overall protein volume conserved to within 6.5%.
-
==About this Structure==
+
3D solution structure of copper and silver-substituted yeast metallothioneins.,Peterson CW, Narula SS, Armitage IM FEBS Lett. 1996 Jan 22;379(1):85-93. PMID:8566237<ref>PMID:8566237</ref>
-
1AQQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with AG as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1AQQ OCA].
+
-
==Reference==
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
3D solution structure of copper and silver-substituted yeast metallothioneins., Peterson CW, Narula SS, Armitage IM, FEBS Lett. 1996 Jan 22;379(1):85-93. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8566237 8566237]
+
</div>
 +
<div class="pdbe-citations 1aqq" style="background-color:#fffaf0;"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
-
[[Category: Single protein]]
+
[[Category: Armitage IM]]
-
[[Category: Armitage, I.M.]]
+
[[Category: Narula SS]]
-
[[Category: Narula, S.S.]]
+
[[Category: Peterson CW]]
-
[[Category: Peterson, C.W.]]
+
-
[[Category: AG]]
+
-
[[Category: copper detoxification]]
+
-
[[Category: metal-thiolate cluster]]
+
-
[[Category: metallothionein]]
+
-
 
+
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 11:03:12 2007''
+

Current revision

AG-SUBSTITUTED METALLOTHIONEIN FROM SACCHAROMYCES CEREVISIAE, NMR, 10 STRUCTURES

PDB ID 1aqq

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1aqq"
Personal tools