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402d

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[[Image:402d.gif|left|200px]]
 
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==5'-R(*CP*GP*CP*CP*AP*GP*CP*G)-3'==
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The line below this paragraph, containing "STRUCTURE_402d", creates the "Structure Box" on the page.
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<StructureSection load='402d' size='340' side='right'caption='[[402d]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[402d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=402D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=402D FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=402d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=402d OCA], [https://pdbe.org/402d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=402d RCSB], [https://www.ebi.ac.uk/pdbsum/402d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=402d ProSAT]</span></td></tr>
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{{STRUCTURE_402d| PDB=402d | SCENE= }}
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</table>
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__TOC__
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'''5'-R(*CP*GP*CP*CP*AP*GP*CP*G)-3''''
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Carter R]]
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==Overview==
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[[Category: Chi Y-I]]
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The crystal structure of the RNA octamer 5'-CGC(CA)GCG-3' has been determined from X-ray diffraction data to 2.3 A resolution. In the crystal, this oligomer forms a self-complementary double helix in the asymmetric unit. Tandem non-Watson-Crick C-A and A-C base pairs comprise an internal loop in the middle of the duplex, which is incorporated with little distortion of the A-form double helix. From the geometry of the C-A base pairs, it is inferred that the adenosine imino group is protonated and donates a hydrogen bond to the carbonyl group of the cytosine. The wobble geometry of the C-A+ base pairs is very similar to that of the common U-G non-Watson-Crick pair.
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[[Category: Holbrook EL]]
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[[Category: Holbrook SR]]
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==About this Structure==
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[[Category: Hung L-W]]
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=402D OCA].
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[[Category: Jang SB]]
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==Reference==
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Structure of an RNA internal loop consisting of tandem C-A+ base pairs., Jang SB, Hung LW, Chi YI, Holbrook EL, Carter RJ, Holbrook SR, Biochemistry. 1998 Aug 25;37(34):11726-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9718295 9718295]
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[[Category: Carter, R.]]
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[[Category: Chi, Y I.]]
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[[Category: Holbrook, E L.]]
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[[Category: Holbrook, S R.]]
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[[Category: Hung, L W.]]
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[[Category: Jang, S B.]]
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[[Category: Rna double helix]]
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[[Category: Rna with tandem c-a+ base pair]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 22:16:06 2008''
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Current revision

5'-R(*CP*GP*CP*CP*AP*GP*CP*G)-3'

PDB ID 402d

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