413d

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[[Image:413d.jpg|left|200px]]
 
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==A'-FORM RNA DOUBLE HELIX IN THE SINGLE CRYSTAL STRUCTURE OF R(UGAGCUUCGGCUC)==
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The line below this paragraph, containing "STRUCTURE_413d", creates the "Structure Box" on the page.
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<StructureSection load='413d' size='340' side='right'caption='[[413d]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[413d]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=373d 373d]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=413D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=413D FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=413d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=413d OCA], [https://pdbe.org/413d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=413d RCSB], [https://www.ebi.ac.uk/pdbsum/413d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=413d ProSAT]</span></td></tr>
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{{STRUCTURE_413d| PDB=413d | SCENE= }}
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</table>
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__TOC__
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'''A'-FORM RNA DOUBLE HELIX IN THE SINGLE CRYSTAL STRUCTURE OF R(UGAGCUUCGGCUC)'''
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Fujii S]]
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==Overview==
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[[Category: Hiroaki H]]
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Here we demonstrate the presence of the A'-RNA conformation using the single crystal structure of a tridecamer: r(UGAGCUUCGGCUC). The average A'-RNA conformation deduced from X-ray fiber diffraction data had only been available previously, but now the presence of the A'-RNA conformation has been found in a single crystal structure for the first time. Statistical analysis showed that the A'-RNA conformation is distinguishable from the A-RNA conformation in a plot of the major groove width against the base pair inclination angle. The major groove of the A'-RNA conformation is wide enough to accommodate a protein or peptide while that of the A-RNA conformation is too narrow to do so. The presence of the A'-RNA conformation is significant for protein-RNA interaction.
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[[Category: Kyogoku Y]]
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[[Category: Sakata T]]
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==About this Structure==
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[[Category: Tanaka T]]
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This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=373d 373d]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=413D OCA].
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[[Category: Tanaka Y]]
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[[Category: Tomita K-I]]
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==Reference==
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[[Category: Uesugi S]]
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A'-form RNA double helix in the single crystal structure of r(UGAGCUUCGGCUC)., Tanaka Y, Fujii S, Hiroaki H, Sakata T, Tanaka T, Uesugi S, Tomita K, Kyogoku Y, Nucleic Acids Res. 1999 Feb 15;27(4):949-55. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9927725 9927725]
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[[Category: Fujii, S.]]
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[[Category: Hiroaki, H.]]
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[[Category: Kyogoku, Y.]]
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[[Category: Sakata, T.]]
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[[Category: Tanaka, T.]]
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[[Category: Tanaka, Y.]]
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[[Category: Tomita, K I.]]
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[[Category: Uesugi, S.]]
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[[Category: A'-rna]]
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[[Category: Double helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 22:16:37 2008''
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Current revision

A'-FORM RNA DOUBLE HELIX IN THE SINGLE CRYSTAL STRUCTURE OF R(UGAGCUUCGGCUC)

PDB ID 413d

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