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2vq6

From Proteopedia

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(New page: 200px <!-- The line below this paragraph, containing "STRUCTURE_2vq6", creates the "Structure Box" on the page. You may change the PDB parameter (which sets the PD...)
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[[Image:2vq6.jpg|left|200px]]
 
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==Torpedo californica acetylcholinesterase complexed with 2-PAM==
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The line below this paragraph, containing "STRUCTURE_2vq6", creates the "Structure Box" on the page.
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<StructureSection load='2vq6' size='340' side='right'caption='[[2vq6]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2vq6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Tetronarce_californica Tetronarce californica]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2vb4 2vb4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VQ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VQ6 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.71&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FP1:N-HYDROXY-1-(1-METHYLPYRIDIN-2(1H)-YLIDENE)METHANAMINE'>FP1</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_2vq6| PDB=2vq6 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vq6 OCA], [https://pdbe.org/2vq6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vq6 RCSB], [https://www.ebi.ac.uk/pdbsum/2vq6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vq6 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ACES_TETCF ACES_TETCF] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vq/2vq6_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vq6 ConSurf].
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<div style="clear:both"></div>
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'''TORPEDO CALIFORNICA ACETYLCHOLINESTERASE COMPLEXED WITH 2-PAM'''
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==See Also==
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*[[Acetylcholinesterase 3D structures|Acetylcholinesterase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2VQ6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2vb4 2vb4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VQ6 OCA].
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[[Category: Large Structures]]
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[[Category: Acetylcholinesterase]]
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[[Category: Tetronarce californica]]
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[[Category: Single protein]]
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[[Category: Harel M]]
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[[Category: Torpedo californica]]
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[[Category: Silman I]]
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[[Category: Harel, M.]]
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[[Category: Sussman JL]]
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[[Category: Silman, I.]]
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[[Category: Sussman, J L.]]
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[[Category: Alternative splicing]]
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[[Category: Anticancer prodrug cpt- 11]]
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[[Category: Cell junction]]
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[[Category: Glycoprotein]]
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[[Category: Gpi-anchor]]
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[[Category: Hydrolase]]
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[[Category: Lipoprotein]]
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[[Category: Membrane]]
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[[Category: Neurotransmitter degradation]]
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[[Category: Serine esterase]]
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[[Category: Synapse]]
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[[Category: Torpedo ache]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 14 11:27:29 2008''
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Current revision

Torpedo californica acetylcholinesterase complexed with 2-PAM

PDB ID 2vq6

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