This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1bvs

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /><applet load="1bvs" size="450" color="white" frame="true" align="right" spinBox="true" caption="1bvs, resolution 3.00&Aring;" /> '''RUVA COMPLEXED TO A ...)
Current revision (05:17, 28 April 2021) (edit) (undo)
(Redirecting to 7oa5)
 
(16 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1bvs.gif|left|200px]]<br /><applet load="1bvs" size="450" color="white" frame="true" align="right" spinBox="true"
+
#REDIRECT [[7oa5]] This PDB entry is obsolete and replaced by 7oa5
-
caption="1bvs, resolution 3.00&Aring;" />
+
-
'''RUVA COMPLEXED TO A HOLLIDAY JUNCTION.'''<br />
+
-
 
+
-
==Overview==
+
-
Holliday junctions occur as intermediates in homologous recombination and, DNA repair. In bacteria, resolution of Holliday junctions is accomplished, by the RuvABC system, consisting of a junction-specific helicase complex, RuvAB, which promotes branch migration, and a junction-specific, endonuclease RuvC, which nicks two strands. The crystal structure of a, complex between the RuvA protein of M. leprae and a synthetic four-way, junction has now been determined. Rather than binding on the open surface, of a RuvA tetramer as previously suggested, the DNA is sandwiched between, two RuvA tetramers, which form a closed octameric shell, stabilized by a, conserved tetramer-tetramer interface. Interactions between the DNA, backbone and helix-hairpin-helix motifs from both tetramers suggest a, mechanism for strand separation promoted by RuvA.
+
-
 
+
-
==About this Structure==
+
-
1BVS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_leprae Mycobacterium leprae]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1BVS OCA].
+
-
 
+
-
==Reference==
+
-
Crystal structure of an octameric RuvA-Holliday junction complex., Roe SM, Barlow T, Brown T, Oram M, Keeley A, Tsaneva IR, Pearl LH, Mol Cell. 1998 Sep;2(3):361-72. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9774974 9774974]
+
-
[[Category: Mycobacterium leprae]]
+
-
[[Category: Single protein]]
+
-
[[Category: Pearl, L.H.]]
+
-
[[Category: Roe, S.M.]]
+
-
[[Category: branch migration]]
+
-
[[Category: dna repair]]
+
-
[[Category: holliday junction resolvase component]]
+
-
 
+
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 11:57:33 2007''
+

Current revision

  1. REDIRECT 7oa5 This PDB entry is obsolete and replaced by 7oa5

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1bvs"
Personal tools