2ro4
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 2ro4 is ON HOLD until Paper Publication Authors: Sullivan, D.M., Bobay, B.G., Kojetin, D.J., Thompson, R.J., Rance, M., Strauch, M.A., Cavanagh, J. ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==RDC-refined Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transition-state Regulator AbrB== | |
| - | + | <StructureSection load='2ro4' size='340' side='right'caption='[[2ro4]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2ro4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RO4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RO4 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ro4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ro4 OCA], [https://pdbe.org/2ro4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ro4 RCSB], [https://www.ebi.ac.uk/pdbsum/2ro4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ro4 ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | '' | + | == Function == |
| + | [https://www.uniprot.org/uniprot/ABRB_BACSU ABRB_BACSU] Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription.<ref>PMID:2504584</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ro/2ro4_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ro4 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bacillus subtilis]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bobay BG]] | ||
| + | [[Category: Cavanagh J]] | ||
| + | [[Category: Kojetin DJ]] | ||
| + | [[Category: Rance M]] | ||
| + | [[Category: Strauch MA]] | ||
| + | [[Category: Sullivan DM]] | ||
| + | [[Category: Thompson RJ]] | ||
Current revision
RDC-refined Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transition-state Regulator AbrB
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