This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2v8b
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 2v8b is ON HOLD Authors: Jakoncic, J., Stojanoff, V. Description: SAD Structure solution of Proteinase K grown in selenate solution ''Page seeded...) |
|||
| (10 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==SAD Structure solution of Proteinase K grown in selenate solution== | |
| + | <StructureSection load='2v8b' size='340' side='right'caption='[[2v8b]], [[Resolution|resolution]] 0.94Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2v8b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Engyodontium_album Engyodontium album]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V8B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V8B FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SE4:SELENATE+ION'>SE4</scene></td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Peptidase_K Peptidase K], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.64 3.4.21.64] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v8b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v8b OCA], [https://pdbe.org/2v8b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v8b RCSB], [https://www.ebi.ac.uk/pdbsum/2v8b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v8b ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/PRTK_TRIAL PRTK_TRIAL]] Hydrolyzes keratin at aromatic and hydrophobic residues. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v8/2v8b_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2v8b ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| - | + | *[[Proteinase|Proteinase]] | |
| - | + | *[[Proteinase 3D structures|Proteinase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Engyodontium album]] | |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Peptidase K]] | ||
| + | [[Category: Jakoncic, J]] | ||
| + | [[Category: Stojanoff, V]] | ||
| + | [[Category: Experimental phasing]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Metal-binding]] | ||
| + | [[Category: Protease]] | ||
| + | [[Category: Serine protease]] | ||
| + | [[Category: Sulfate]] | ||
| + | [[Category: Zymogen]] | ||
Current revision
SAD Structure solution of Proteinase K grown in selenate solution
| |||||||||||
