3ceq
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3ceq is ON HOLD Authors: Zhu, H., Shen, Y., MacKenzie, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Struc...) |
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The TPR domain of Human Kinesin Light Chain 2 (hKLC2)== |
| + | <StructureSection load='3ceq' size='340' side='right'caption='[[3ceq]], [[Resolution|resolution]] 2.75Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3ceq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CEQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CEQ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ceq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ceq OCA], [https://pdbe.org/3ceq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ceq RCSB], [https://www.ebi.ac.uk/pdbsum/3ceq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ceq ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/KLC2_HUMAN KLC2_HUMAN] Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ce/3ceq_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ceq ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| - | + | *[[Kinesin 3D Structures|Kinesin 3D Structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Homo sapiens]] | |
| - | + | [[Category: Large Structures]] | |
| + | [[Category: Arrowsmith CH]] | ||
| + | [[Category: Bochkarev A]] | ||
| + | [[Category: Bountra C]] | ||
| + | [[Category: Edwards AM]] | ||
| + | [[Category: MacKenzie F]] | ||
| + | [[Category: Park H]] | ||
| + | [[Category: Shen Y]] | ||
| + | [[Category: Weigelt J]] | ||
| + | [[Category: Zhu H]] | ||
Current revision
The TPR domain of Human Kinesin Light Chain 2 (hKLC2)
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bochkarev A | Bountra C | Edwards AM | MacKenzie F | Park H | Shen Y | Weigelt J | Zhu H
