3d4p

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(New page: '''Unreleased structure''' The entry 3d4p is ON HOLD Authors: Schramm, V.L., Almo, S.C., Gutierrez, J.A., Ho, M. Description: Crystal structure of Lactate Dehydrogenase from Staphyloco...)
Current revision (08:56, 15 November 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 3d4p is ON HOLD
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==Crystal structure of Lactate Dehydrogenase from Staphylococcus Aureus complexed with NAD and pyruvate==
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<StructureSection load='3d4p' size='340' side='right'caption='[[3d4p]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3d4p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_COL Staphylococcus aureus subsp. aureus COL]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D4P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D4P FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d4p OCA], [https://pdbe.org/3d4p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d4p RCSB], [https://www.ebi.ac.uk/pdbsum/3d4p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d4p ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LDH1_STAAC LDH1_STAAC] Appears to be the primary factor that allows S.aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells.<ref>PMID:18356528</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d4/3d4p_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3d4p ConSurf].
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<div style="clear:both"></div>
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Authors: Schramm, V.L., Almo, S.C., Gutierrez, J.A., Ho, M.
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==See Also==
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*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
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Description: Crystal structure of Lactate Dehydrogenase from Staphylococcus Aureus complexed with NAD and pyruvate
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== References ==
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<references/>
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__TOC__
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 09:37:06 2008''
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Staphylococcus aureus subsp. aureus COL]]
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[[Category: Almo SC]]
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[[Category: Gutierrez JA]]
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[[Category: Ho M]]
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[[Category: Schramm VL]]

Current revision

Crystal structure of Lactate Dehydrogenase from Staphylococcus Aureus complexed with NAD and pyruvate

PDB ID 3d4p

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