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2jvh

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[[Image:2jvh.jpg|left|200px]]
 
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==Structure of C3-binding domain 4 of S. aureus protein Sbi==
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The line below this paragraph, containing "STRUCTURE_2jvh", creates the "Structure Box" on the page.
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<StructureSection load='2jvh' size='340' side='right'caption='[[2jvh]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2jvh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JVH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JVH FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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-->
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jvh OCA], [https://pdbe.org/2jvh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jvh RCSB], [https://www.ebi.ac.uk/pdbsum/2jvh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jvh ProSAT]</span></td></tr>
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{{STRUCTURE_2jvh| PDB=2jvh | SCENE= }}
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</table>
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== Function ==
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'''Structure of C3-binding domain 4 of S. aureus protein Sbi'''
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[https://www.uniprot.org/uniprot/SBI_STAAM SBI_STAAM] Plays a role in the inhibition of both the innate and adaptive immune responses. Possesses two N-terminal domains that bind the Fc region of IgG and two domains that form a tripartite complex with complement factors C3b and CFH. By recruiting CFH and C3b, the secreted form acts as a potent complement inhibitor of the alternative pathway-mediated lysis.[UniProtKB:A6QJQ7]<ref>PMID:18550524</ref>
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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2JVH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JVH OCA].
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</StructureSection>
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[[Category: Single protein]]
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[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: Bagby, S.]]
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[[Category: Bagby S]]
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[[Category: Burman, J.]]
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[[Category: Burman J]]
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[[Category: Clark, E A.]]
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[[Category: Clark EA]]
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[[Category: Elsen, J M.H van den.]]
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[[Category: Upadhyay A]]
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[[Category: Upadhyay, A.]]
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[[Category: Van den Elsen JMH]]
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[[Category: Immune system]]
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[[Category: Three helix bundle]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 10:42:54 2008''
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Current revision

Structure of C3-binding domain 4 of S. aureus protein Sbi

PDB ID 2jvh

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