2vsn

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[[Image:2vsn.jpg|left|200px]]
 
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==Structure and topological arrangement of an O-GlcNAc transferase homolog: insight into molecular control of intracellular glycosylation==
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The line below this paragraph, containing "STRUCTURE_2vsn", creates the "Structure Box" on the page.
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<StructureSection load='2vsn' size='340' side='right'caption='[[2vsn]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2vsn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Xanthomonas_campestris_pv._campestris_str._8004 Xanthomonas campestris pv. campestris str. 8004]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VSN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VSN FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
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{{STRUCTURE_2vsn| PDB=2vsn | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vsn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vsn OCA], [https://pdbe.org/2vsn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vsn RCSB], [https://www.ebi.ac.uk/pdbsum/2vsn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vsn ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A0H2XAK3_XANC8 A0A0H2XAK3_XANC8]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vs/2vsn_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vsn ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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N-Acetylglucosamine (O-GlcNAc) modification of proteins provides a mechanism for the control of diverse cellular processes through a dynamic interplay with phosphorylation. UDP-GlcNAc:polypeptidyl transferase (OGT) catalyzes O-GlcNAc addition. The structure of an intact OGT homolog and kinetic analysis of human OGT variants reveal a contiguous superhelical groove that directs substrates to the active site.
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'''STRUCTURE AND TOPOLOGICAL ARRANGEMENT OF AN O-GLCNAC TRANSFERASE HOMOLOG: INSIGHT INTO MOLECULAR CONTROL OF INTRACELLULAR GLYCOSYLATION'''
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Structure of an O-GlcNAc transferase homolog provides insight into intracellular glycosylation.,Martinez-Fleites C, Macauley MS, He Y, Shen DL, Vocadlo DJ, Davies GJ Nat Struct Mol Biol. 2008 Jul;15(7):764-5. Epub 2008 Jun 8. PMID:18536723<ref>PMID:18536723</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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==About this Structure==
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</div>
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2VSN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Xanthomonas_campestris_pv._campestris Xanthomonas campestris pv. campestris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VSN OCA].
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<div class="pdbe-citations 2vsn" style="background-color:#fffaf0;"></div>
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[[Category: Single protein]]
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== References ==
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[[Category: Xanthomonas campestris pv. campestris]]
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<references/>
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[[Category: Davies, G J.]]
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__TOC__
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[[Category: He, Y.]]
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</StructureSection>
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[[Category: Macauley, M S.]]
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[[Category: Large Structures]]
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[[Category: Martinez-Fleites, C.]]
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[[Category: Xanthomonas campestris pv. campestris str. 8004]]
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[[Category: Shen, D.]]
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[[Category: Davies GJ]]
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[[Category: Vocadlo, D.]]
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[[Category: He Y]]
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[[Category: Glcnac]]
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[[Category: Macauley MS]]
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[[Category: Glycosyl transferase]]
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[[Category: Martinez-Fleites C]]
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[[Category: N- acetylglucosamine]]
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[[Category: Shen D]]
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[[Category: O-glycosylation]]
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[[Category: Vocadlo D]]
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[[Category: Ogt]]
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[[Category: Tpr]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 10:45:56 2008''
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Current revision

Structure and topological arrangement of an O-GlcNAc transferase homolog: insight into molecular control of intracellular glycosylation

PDB ID 2vsn

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