2zof

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[[Image:2zof.jpg|left|200px]]
 
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==Crystal structure of mouse carnosinase CN2 complexed with MN and bestatin==
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The line below this paragraph, containing "STRUCTURE_2zof", creates the "Structure Box" on the page.
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<StructureSection load='2zof' size='340' side='right'caption='[[2zof]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2zof]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZOF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZOF FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BES:2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC+ACID'>BES</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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{{STRUCTURE_2zof| PDB=2zof | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zof OCA], [https://pdbe.org/2zof PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zof RCSB], [https://www.ebi.ac.uk/pdbsum/2zof PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zof ProSAT]</span></td></tr>
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</table>
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'''Crystal structure of mouse carnosinase CN2 complexed with MN and bestatin'''
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== Function ==
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[https://www.uniprot.org/uniprot/CNDP2_MOUSE CNDP2_MOUSE] Hydrolyzes a variety of dipeptides including L-carnosine. Has a strong preference for Cys-Gly (By similarity).
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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2ZOF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZOF OCA].
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Check<jmol>
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[[Category: Cytosol nonspecific dipeptidase]]
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zo/2zof_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zof ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Single protein]]
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[[Category: Kusunoki M]]
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[[Category: Kusunoki, M.]]
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[[Category: Okumura N]]
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[[Category: Okumura, N.]]
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[[Category: Unno H]]
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[[Category: Unno, H.]]
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[[Category: Yamashita T]]
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[[Category: Yamashita, T.]]
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[[Category: Bestatin]]
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[[Category: Carboxypeptidase]]
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[[Category: Carnosinase]]
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[[Category: Cn2]]
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[[Category: Cndp dipeptidase 2]]
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[[Category: Cndp2]]
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[[Category: Hydrolase]]
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[[Category: L-carnosine]]
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[[Category: Metal-binding]]
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[[Category: Metallopeptidase]]
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[[Category: Metalloprotease]]
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[[Category: Mn]]
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[[Category: Protease]]
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[[Category: Protein-inhibitor complex]]
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[[Category: Zinc]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 10:46:09 2008''
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Current revision

Crystal structure of mouse carnosinase CN2 complexed with MN and bestatin

PDB ID 2zof

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OCA

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