Template:STRUCTURE 1hvy

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Current revision

1hvy, resolution 1.90Å ()

Ligands:

, ,

Non-Standard Residues:

Activity:

Thymidylate synthase, with EC number 2.1.1.45

Structural annotation:
Resources:	CATH : 1Hvya00, 1Hvyb00, 1Hvyc00, 1Hvyd00 InterPro : Ipr020940, Ipr000398, Ipr023451 Pfam : PF00303 SCOP : d1hvya_, d1hvyb_, d1hvyc_, d1hvyd_

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/Template:STRUCTURE_1hvy"

@@ Line 1: / Line 1: @@
-{{StructureD
+{{Structure
-|PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|1hvy, resolution 1.90&Aring; (<scene name='initialview01'>initial scene</scene>)}}}
+|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1hvy]], [[Resolution|resolution]] 1.90&Aring; (<scene name='initialview01'>default scene</scene>)}}}
 |LIGAND= <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=D16:TOMUDEX'>D16</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene>
 |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span>
-|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00351 TS_Pyrimidine_HMase]</span>
 |NONSTDRES=<scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hvy OCA], [http://www.ebi.ac.uk/pdbsum/1hvy PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1hvy RCSB]</span>
+|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hvy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hvy RCSB], [http://www.ebi.ac.uk/pdbsum/1hvy PDBsum]</span>
-|FUNCTION={{GO|id=GO:0008168 | text = methyltransferase activity}}{{GO|id=GO:0004799 | text = thymidylate synthase activity}}{{GO|id=GO:0016740 | text = transferase activity}}
+|SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/domain/1hvyA00 1Hvya00], [http://www.cathdb.info/domain/1hvyB00 1Hvyb00], [http://www.cathdb.info/domain/1hvyC00 1Hvyc00], [http://www.cathdb.info/domain/1hvyD00 1Hvyd00]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR020940 Ipr020940], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000398 Ipr000398], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR023451 Ipr023451]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00303 PF00303]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=41049 d1hvya_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=41050 d1hvyb_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=41051 d1hvyc_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=41052 d1hvyd_]</span>
-|PROCESS={{GO|id=GO:0009157 | text = deoxyribonucleoside monophosphate biosynthetic process}}{{GO|id=GO:0006139 | text = nucleobase, nucleoside, nucleotide and nucleic acid metabolic process}}{{GO|id=GO:0048015 | text = phosphoinositide-mediated signaling}}{{GO|id=GO:0009165 | text = nucleotide biosynthetic process}}{{GO|id=GO:0006231 | text = dTMP biosynthetic process}}{{GO|id=GO:0006260 | text = DNA replication}}{{GO|id=GO:0006281 | text = DNA repair}}
+|uPDB=1HVY|CONSURF={{!}}-
-|SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hvyA00 1Hvya00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hvyB00 1Hvyb00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hvyC00 1Hvyc00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hvyD00 1Hvyd00]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR014370 Ipr014370], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000398 Ipr000398]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00303 PF00303]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=41049 d1hvya_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=41050 d1hvyb_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=41051 d1hvyc_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=41052 d1hvyd_]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P04818 P04818]</span>
+{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
-|FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=P04818 P04818]</span>
+{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
+{{!}} '''Toggle Conservation Colors:'''
+{{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}}
+Rows = identical sequences:
+<jmol>
+<jmolButton>
+<script></script>
+<text>A [x]</text>
+<name>jmb_1hvy_A</name>
+<title>toggle chain A</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>B [x]</text>
+<name>jmb_1hvy_B</name>
+<title>toggle chain B</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>C [x]</text>
+<name>jmb_1hvy_C</name>
+<title>toggle chain C</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>D [x]</text>
+<name>jmb_1hvy_D</name>
+<title>toggle chain D</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
 }}

Template:STRUCTURE 1hvy

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