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Template:STRUCTURE 1x70

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{{StructureD
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{{Structure
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|PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|1x70, resolution 2.10&Aring; (<scene name='initialview01'>initial scene</scene>)}}}
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|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1x70]], [[Resolution|resolution]] 2.10&Aring; (<scene name='initialview01'>default scene</scene>)}}}
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|LIGAND= <scene name='pdbligand=715:(2R)-4-OXO-4-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE'>715</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:SUGAR+(N-ACETYL-D-GLUCOSAMINE)'>NAG</scene>
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|LIGAND= <scene name='pdbligand=715:(2R)-4-OXO-4-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE'>715</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Dipeptidyl-peptidase_IV Dipeptidyl-peptidase IV], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.14.5 3.4.14.5] </span>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Dipeptidyl-peptidase_IV Dipeptidyl-peptidase IV], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.14.5 3.4.14.5] </span>
|GENE= DPP4, ADCP2, CD26 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= DPP4, ADCP2, CD26 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00326 Peptidase_S9], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00930 DPPIV_N]</span>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x70 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1x70 RCSB], [http://www.ebi.ac.uk/pdbsum/1x70 PDBsum]</span>
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|NONSTDRES=<scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>
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|SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/domain/1x70A01 1X70A01], [http://www.cathdb.info/domain/1x70A02 1X70A02], [http://www.cathdb.info/domain/1x70B02 1X70B02], [http://www.cathdb.info/domain/1x70B01 1X70B01]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002469 Ipr002469], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002471 Ipr002471], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001375 Ipr001375]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00930 PF00930], [http://pfam.sanger.ac.uk/family?acc=PF00326 PF00326]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=121765 d1x70a2], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=121764 d1x70a1], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=121767 d1x70b2], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=121766 d1x70b1]</span>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x70 OCA], [http://www.ebi.ac.uk/pdbsum/1x70 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1x70 RCSB]</span>
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|uPDB=1X70|CONSURF={{!}}-
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|FUNCTION={{GO|id=GO:0008233 | text = peptidase activity}}{{GO|id=GO:0004274 | text = dipeptidyl-peptidase IV activity}}{{GO|id=GO:0004287 | text = prolyl oligopeptidase activity}}{{GO|id=GO:0016787 | text = hydrolase activity}}{{GO|id=GO:0004177 | text = aminopeptidase activity}}{{GO|id=GO:0008236 | text = serine-type peptidase activity}}{{GO|id=GO:0004252 | text = serine-type endopeptidase activity}}
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{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
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|PROCESS={{GO|id=GO:0006508 | text = proteolysis}}{{GO|id=GO:0006955 | text = immune response}}
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{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
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|COMPONENT={{GO|id=GO:0016020 | text = membrane}}{{GO|id=GO:0016021 | text = integral to membrane}}
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{{!}} '''Toggle Conservation Colors:'''
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|SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1x70A01 1X70A01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1x70A02 1X70A02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1x70B01 1X70B01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1x70B02 1X70B02]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002471 Ipr002471], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001375 Ipr001375], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002469 Ipr002469]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00326 PF00326], [http://pfam.sanger.ac.uk/family?acc=PF00930 PF00930]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P27487 P27487]</span>
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{{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}}
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|FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=P27487 P27487]</span>
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Rows = identical sequences:
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<jmol>
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<jmolButton>
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<script></script>
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<text>A [x]</text>
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<name>jmb_1x70_A</name>
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<title>toggle chain A</title>
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<jsscript>ConsurfChainButton(elementClicked)</jsscript>
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<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
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</jmolButton>
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</jmol>
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<jmol>
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<jmolButton>
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<script></script>
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<text>B [x]</text>
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<name>jmb_1x70_B</name>
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<title>toggle chain B</title>
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<jsscript>ConsurfChainButton(elementClicked)</jsscript>
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<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
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</jmolButton>
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</jmol>
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}}
}}

Current revision

Drag the structure with the mouse to rotate
1x70, resolution 2.10Å ()
Ligands: , , ,
Gene: DPP4, ADCP2, CD26 (Homo sapiens)
Activity: Dipeptidyl-peptidase IV, with EC number 3.4.14.5
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml


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