Template:STRUCTURE 2clt

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{{StructureD
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{{Structure
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|PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|2clt, resolution 2.67&Aring; (<scene name='initialview01'>initial scene</scene>)}}}
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|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[2clt]], [[Resolution|resolution]] 2.67&Aring; (<scene name='initialview01'>default scene</scene>)}}}
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|SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Chain+B'>AC1</scene>
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|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Interstitial_collagenase Interstitial collagenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.7 3.4.24.7] </span>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Interstitial_collagenase Interstitial collagenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.7 3.4.24.7] </span>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00094 HX], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04278 ZnMc_MMP]</span>
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|RELATEDENTRY=[[1ayk|1ayk]], [[1cge|1cge]], [[1cgf|1cgf]], [[1cgl|1cgl]], [[1hfc|1hfc]], [[1su3|1su3]], [[2ayk|2ayk]], [[2tcl|2tcl]], [[3ayk|3ayk]], [[4ayk|4ayk]], [[966c|966c]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2clt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2clt OCA], [http://www.ebi.ac.uk/pdbsum/2clt PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2clt RCSB]</span>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2clt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2clt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2clt RCSB], [http://www.ebi.ac.uk/pdbsum/2clt PDBsum]</span>
|FUNCTION={{GO|id=GO:0008270 | text = zinc ion binding}}{{GO|id=GO:0016787 | text = hydrolase activity}}{{GO|id=GO:0008233 | text = peptidase activity}}{{GO|id=GO:0046872 | text = metal ion binding}}{{GO|id=GO:0003824 | text = catalytic activity}}{{GO|id=GO:0005509 | text = calcium ion binding}}{{GO|id=GO:0008133 | text = collagenase activity}}{{GO|id=GO:0008237 | text = metallopeptidase activity}}{{GO|id=GO:0004232 | text = interstitial collagenase activity}}{{GO|id=GO:0004222 | text = metalloendopeptidase activity}}
|FUNCTION={{GO|id=GO:0008270 | text = zinc ion binding}}{{GO|id=GO:0016787 | text = hydrolase activity}}{{GO|id=GO:0008233 | text = peptidase activity}}{{GO|id=GO:0046872 | text = metal ion binding}}{{GO|id=GO:0003824 | text = catalytic activity}}{{GO|id=GO:0005509 | text = calcium ion binding}}{{GO|id=GO:0008133 | text = collagenase activity}}{{GO|id=GO:0008237 | text = metallopeptidase activity}}{{GO|id=GO:0004232 | text = interstitial collagenase activity}}{{GO|id=GO:0004222 | text = metalloendopeptidase activity}}
|PROCESS={{GO|id=GO:0008152 | text = metabolic process}}{{GO|id=GO:0030574 | text = collagen catabolic process}}{{GO|id=GO:0006508 | text = proteolysis}}
|PROCESS={{GO|id=GO:0008152 | text = metabolic process}}{{GO|id=GO:0030574 | text = collagen catabolic process}}{{GO|id=GO:0006508 | text = proteolysis}}
|COMPONENT={{GO|id=GO:0005578 | text = proteinaceous extracellular matrix}}{{GO|id=GO:0005615 | text = extracellular space}}
|COMPONENT={{GO|id=GO:0005578 | text = proteinaceous extracellular matrix}}{{GO|id=GO:0005615 | text = extracellular space}}
|SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=2cltA02 2Clta02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=2cltA01 2Clta01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=2cltB01 2Cltb01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=2cltB02 2Cltb02]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002477 Ipr002477], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001818 Ipr001818], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR006026 Ipr006026], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000585 Ipr000585], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR006025 Ipr006025]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00045 PF00045], [http://pfam.sanger.ac.uk/family?acc=PF00413 PF00413]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P03956 P03956]</span>
|SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=2cltA02 2Clta02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=2cltA01 2Clta01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=2cltB01 2Cltb01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=2cltB02 2Cltb02]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002477 Ipr002477], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001818 Ipr001818], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR006026 Ipr006026], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000585 Ipr000585], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR006025 Ipr006025]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00045 PF00045], [http://pfam.sanger.ac.uk/family?acc=PF00413 PF00413]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P03956 P03956]</span>
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|FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=P03956 P03956]</span>
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|uPDB=2CLT|CONSURF={{!}}-
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{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
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{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
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{{!}} '''Toggle Conservation Colors:'''
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{{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}}
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Rows = identical sequences:
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<jmol>
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<jmolButton>
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<script></script>
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<text>A [x]</text>
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<name>jmb_2clt_A</name>
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<title>toggle chain A</title>
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<jsscript>ConsurfChainButton(elementClicked)</jsscript>
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<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
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</jmolButton>
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</jmol>
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<jmol>
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<jmolButton>
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<script></script>
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<text>B [x]</text>
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<name>jmb_2clt_B</name>
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<title>toggle chain B</title>
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<jsscript>ConsurfChainButton(elementClicked)</jsscript>
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<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
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</jmolButton>
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</jmol>
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}}
}}

Current revision

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2clt, resolution 2.67Å ()
Ligands: ,
Activity: Interstitial collagenase, with EC number 3.4.24.7
Related: 1ayk, 1cge, 1cgf, 1cgl, 1hfc, 1su3, 2ayk, 2tcl, 3ayk, 4ayk, 966c
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml


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