1de2
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="1de2" size="450" color="white" frame="true" align="right" spinBox="true" caption="1de2" /> '''NMR STRUCTURES OF REDUCED BACTERIOPHAGE T4 G...) |
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| - | [[Image:1de2.jpg|left|200px]]<br /><applet load="1de2" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1de2" /> | ||
| - | '''NMR STRUCTURES OF REDUCED BACTERIOPHAGE T4 GLUTAREDOXIN'''<br /> | ||
| - | == | + | ==NMR STRUCTURES OF REDUCED BACTERIOPHAGE T4 GLUTAREDOXIN== |
| - | + | <StructureSection load='1de2' size='340' side='right'caption='[[1de2]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[1de2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DE2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DE2 FirstGlance]. <br> |
| - | Solution | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1de2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1de2 OCA], [https://pdbe.org/1de2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1de2 RCSB], [https://www.ebi.ac.uk/pdbsum/1de2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1de2 ProSAT]</span></td></tr> | |
| - | [ | + | </table> |
| - | + | == Function == | |
| - | [ | + | [https://www.uniprot.org/uniprot/GLRX_BPT4 GLRX_BPT4] Serves as a reducing agent for the phage-induced ribonucleotide reductase, but not for the bacterial ones. This specificity may be the result of sequence differences around the redox-active disulfide bond. The oxidized form accepts electrons from bacterial glutathione and will, in turn, reduce other small disulfides. Can also be reduced by NADPH and by bacterial thioredoxin reductase.<ref>PMID:8440680</ref> |
| - | [[ | + | == Evolutionary Conservation == |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | + | Check<jmol> | |
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/de/1de2_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1de2 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia virus T4]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Wang Y]] | ||
| + | [[Category: Wishart DS]] | ||
Current revision
NMR STRUCTURES OF REDUCED BACTERIOPHAGE T4 GLUTAREDOXIN
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