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1aew

From Proteopedia

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[[Image:1aew.png|left|200px]]
 
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==L-CHAIN HORSE APOFERRITIN==
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The line below this paragraph, containing "STRUCTURE_1aew", creates the "Structure Box" on the page.
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<StructureSection load='1aew' size='340' side='right'caption='[[1aew]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1aew]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. The November 2002 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Ferritin and Transferrin'' by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2002_11 10.2210/rcsb_pdb/mom_2002_11]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AEW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AEW FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
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{{STRUCTURE_1aew| PDB=1aew | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1aew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1aew OCA], [https://pdbe.org/1aew PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1aew RCSB], [https://www.ebi.ac.uk/pdbsum/1aew PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1aew ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FRIL_HORSE FRIL_HORSE] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ae/1aew_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1aew ConSurf].
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<div style="clear:both"></div>
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'''L-CHAIN HORSE APOFERRITIN'''
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==See Also==
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*[[Ferritin 3D structures|Ferritin 3D structures]]
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__TOC__
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{{ABSTRACT_9159481}}
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</StructureSection>
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==About this Structure==
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1AEW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. The following page contains interesting information on the relation of 1AEW with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb35_1.html Ferritin and Transferrin]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AEW OCA].
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[[Category: Equus caballus]]
[[Category: Equus caballus]]
[[Category: Ferritin and Transferrin]]
[[Category: Ferritin and Transferrin]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Artymiuk, P J.]]
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[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Harrison, P M.]]
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[[Category: Artymiuk PJ]]
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[[Category: Hempstead, P D.]]
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[[Category: Harrison PM]]
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[[Category: Lawson, D M.]]
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[[Category: Hempstead PD]]
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[[Category: Yewdall, S J.]]
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[[Category: Lawson DM]]
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[[Category: Acetylation]]
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[[Category: Yewdall SJ]]
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[[Category: Iron storage]]
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[[Category: Multigene family]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 26 17:02:53 2008''
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Current revision

L-CHAIN HORSE APOFERRITIN

PDB ID 1aew

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