1a1s

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{{Seed}}
 
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[[Image:1a1s.png|left|200px]]
 
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==ORNITHINE CARBAMOYLTRANSFERASE FROM PYROCOCCUS FURIOSUS==
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The line below this paragraph, containing "STRUCTURE_1a1s", creates the "Structure Box" on the page.
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<StructureSection load='1a1s' size='340' side='right'caption='[[1a1s]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1a1s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A1S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A1S FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a1s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a1s OCA], [https://pdbe.org/1a1s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a1s RCSB], [https://www.ebi.ac.uk/pdbsum/1a1s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a1s ProSAT]</span></td></tr>
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{{STRUCTURE_1a1s| PDB=1a1s | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/OTCA_PYRFU OTCA_PYRFU] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis.<ref>PMID:9288930</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a1/1a1s_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1a1s ConSurf].
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<div style="clear:both"></div>
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===ORNITHINE CARBAMOYLTRANSFERASE FROM PYROCOCCUS FURIOSUS===
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==See Also==
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*[[Ornithine carbamoyltransferase 3D structures|Ornithine carbamoyltransferase 3D structures]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_9501170}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 9501170 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_9501170}}
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==About this Structure==
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1A1S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A1S OCA].
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==Reference==
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The crystal structure of Pyrococcus furiosus ornithine carbamoyltransferase reveals a key role for oligomerization in enzyme stability at extremely high temperatures., Villeret V, Clantin B, Tricot C, Legrain C, Roovers M, Stalon V, Glansdorff N, Van Beeumen J, Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):2801-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9501170 9501170]
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[[Category: Ornithine carbamoyltransferase]]
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[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
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[[Category: Single protein]]
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[[Category: Clantin B]]
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[[Category: Beeumen, J Van.]]
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[[Category: Glansdorff N]]
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[[Category: Clantin, B.]]
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[[Category: Legrain C]]
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[[Category: Glansdorff, N.]]
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[[Category: Roovers M]]
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[[Category: Legrain, C.]]
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[[Category: Stalon V]]
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[[Category: Roovers, M.]]
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[[Category: Tricot C]]
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[[Category: Stalon, V.]]
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[[Category: Van Beeumen J]]
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[[Category: Tricot, C.]]
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[[Category: Villeret V]]
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[[Category: Villeret, V.]]
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[[Category: Transcarbamylase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 15:48:33 2008''
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Current revision

ORNITHINE CARBAMOYLTRANSFERASE FROM PYROCOCCUS FURIOSUS

PDB ID 1a1s

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