This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1adv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:29, 7 February 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1adv.png|left|200px]]
 
-
<!--
+
==EARLY E2A DNA-BINDING PROTEIN==
-
The line below this paragraph, containing "STRUCTURE_1adv", creates the "Structure Box" on the page.
+
<StructureSection load='1adv' size='340' side='right'caption='[[1adv]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1adv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_adenovirus_5 Human adenovirus 5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ADV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ADV FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
{{STRUCTURE_1adv| PDB=1adv | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1adv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1adv OCA], [https://pdbe.org/1adv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1adv RCSB], [https://www.ebi.ac.uk/pdbsum/1adv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1adv ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/DNB2_ADE05 DNB2_ADE05] Binds cooperatively single-stranded DNA in a sequence-independent manner. Involved in DNA-replication, regulation of mRNA formation, and host-range specificity. Zinc is required for DNA binding.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ad/1adv_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1adv ConSurf].
 +
<div style="clear:both"></div>
-
===EARLY E2A DNA-BINDING PROTEIN===
+
==See Also==
-
 
+
*[[Single-stranded DNA-binding protein 3D structures|Single-stranded DNA-binding protein 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_8632448}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 8632448 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_8632448}}
+
-
 
+
-
==About this Structure==
+
-
1ADV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_adenovirus_5 Human adenovirus 5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ADV OCA].
+
-
 
+
-
==Reference==
+
-
Alternative arrangements of the protein chain are possible for the adenovirus single-stranded DNA binding protein., Kanellopoulos PN, Tsernoglou D, van der Vliet PC, Tucker PA, J Mol Biol. 1996 Mar 22;257(1):1-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8632448 8632448]
+
[[Category: Human adenovirus 5]]
[[Category: Human adenovirus 5]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Kanellopoulos, P N.]]
+
[[Category: Kanellopoulos PN]]
-
[[Category: Tsernoglou, D.]]
+
[[Category: Tsernoglou D]]
-
[[Category: Tucker, P A.]]
+
[[Category: Tucker PA]]
-
[[Category: Vliet, P C.Van Der.]]
+
[[Category: Van Der Vliet PC]]
-
[[Category: Dna-binding protein]]
+
-
[[Category: Ssdna binding protein]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 16:38:33 2008''
+

Current revision

EARLY E2A DNA-BINDING PROTEIN

PDB ID 1adv

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools