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1am7

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{{Seed}}
 
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[[Image:1am7.png|left|200px]]
 
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<!--
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==Lysozyme from bacteriophage lambda==
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The line below this paragraph, containing "STRUCTURE_1am7", creates the "Structure Box" on the page.
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<StructureSection load='1am7' size='340' side='right'caption='[[1am7]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1am7]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AM7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AM7 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=TRN:NZ2-TRYPTOPHAN'>TRN</scene></td></tr>
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{{STRUCTURE_1am7| PDB=1am7 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1am7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1am7 OCA], [https://pdbe.org/1am7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1am7 RCSB], [https://www.ebi.ac.uk/pdbsum/1am7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1am7 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ENLYS_LAMBD ENLYS_LAMBD] Endolysin with transglycosylase activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.[HAMAP-Rule:MF_04109]<ref>PMID:10556513</ref> <ref>PMID:24113139</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/am/1am7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1am7 ConSurf].
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<div style="clear:both"></div>
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===LYSOZYME FROM BACTERIOPHAGE LAMBDA===
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==See Also==
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*[[Lysozyme 3D structures|Lysozyme 3D structures]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_9514719}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 9514719 is the PubMed ID number.
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</StructureSection>
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[[Category: Escherichia virus Lambda]]
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{{ABSTRACT_PUBMED_9514719}}
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[[Category: Large Structures]]
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[[Category: Declercq JP]]
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==About this Structure==
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[[Category: Evrard C]]
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1AM7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AM7 OCA].
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[[Category: Fastrez J]]
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==Reference==
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Crystal structure of the lysozyme from bacteriophage lambda and its relationship with V and C-type lysozymes., Evrard C, Fastrez J, Declercq JP, J Mol Biol. 1998 Feb 13;276(1):151-64. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9514719 9514719]
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[[Category: Enterobacteria phage lambda]]
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[[Category: Single protein]]
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[[Category: Declercq, J P.]]
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[[Category: Evrard, C.]]
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[[Category: Fastrez, J.]]
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[[Category: Evolution]]
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[[Category: Glycosidase]]
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[[Category: Lysozyme]]
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[[Category: Transglycosylase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 17:08:23 2008''
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Current revision

Lysozyme from bacteriophage lambda

PDB ID 1am7

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