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1anb

From Proteopedia

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{{Seed}}
 
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[[Image:1anb.png|left|200px]]
 
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<!--
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==ANIONIC TRYPSIN MUTANT WITH SER 214 REPLACED BY GLU==
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The line below this paragraph, containing "STRUCTURE_1anb", creates the "Structure Box" on the page.
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<StructureSection load='1anb' size='340' side='right'caption='[[1anb]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1anb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_rattus Rattus rattus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ANB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ANB FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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{{STRUCTURE_1anb| PDB=1anb | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1anb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1anb OCA], [https://pdbe.org/1anb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1anb RCSB], [https://www.ebi.ac.uk/pdbsum/1anb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1anb ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRY2_RAT TRY2_RAT]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/an/1anb_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1anb ConSurf].
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<div style="clear:both"></div>
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===ANIONIC TRYPSIN MUTANT WITH SER 214 REPLACED BY GLU===
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==See Also==
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*[[Trypsin 3D structures|Trypsin 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_1554694}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 1554694 is the PubMed ID number.
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-->
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{{ABSTRACT_PUBMED_1554694}}
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==About this Structure==
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1ANB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_rattus Rattus rattus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ANB OCA].
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==Reference==
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Perturbing the polar environment of Asp102 in trypsin: consequences of replacing conserved Ser214., McGrath ME, Vasquez JR, Craik CS, Yang AS, Honig B, Fletterick RJ, Biochemistry. 1992 Mar 31;31(12):3059-64. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1554694 1554694]
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[[Category: Rattus rattus]]
[[Category: Rattus rattus]]
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[[Category: Single protein]]
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[[Category: Fletterick RJ]]
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[[Category: Trypsin]]
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[[Category: Mcgrath ME]]
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[[Category: Fletterick, R J.]]
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[[Category: Mcgrath, M E.]]
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[[Category: Anionic]]
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[[Category: Hydrolase]]
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[[Category: Serine protease]]
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[[Category: Trypsin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 17:12:34 2008''
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Current revision

ANIONIC TRYPSIN MUTANT WITH SER 214 REPLACED BY GLU

PDB ID 1anb

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