1ayi

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{{Seed}}
 
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[[Image:1ayi.png|left|200px]]
 
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==COLICIN E7 IMMUNITY PROTEIN IM7==
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The line below this paragraph, containing "STRUCTURE_1ayi", creates the "Structure Box" on the page.
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<StructureSection load='1ayi' size='340' side='right'caption='[[1ayi]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ayi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AYI FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ayi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ayi OCA], [https://pdbe.org/1ayi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ayi RCSB], [https://www.ebi.ac.uk/pdbsum/1ayi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ayi ProSAT]</span></td></tr>
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{{STRUCTURE_1ayi| PDB=1ayi | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IMM7_ECOLX IMM7_ECOLX] This protein is able to protect a cell, which harbors the plasmid ColE7 encoding colicin E7, against colicin E7, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity. Dimeric ImmE7 may possess a RNase activity that cleaves its own mRNA at a specific site and thus autoregulates translational expression of the downstream ceiE7 gene as well as degradation of the upstream ceaE7 mRNA.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ay/1ayi_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ayi ConSurf].
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<div style="clear:both"></div>
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===COLICIN E7 IMMUNITY PROTEIN IM7===
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==See Also==
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*[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_9639578}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 9639578 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9639578}}
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==About this Structure==
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1AYI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AYI OCA].
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==Reference==
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A structural comparison of the colicin immunity proteins Im7 and Im9 gives new insights into the molecular determinants of immunity-protein specificity., Dennis CA, Videler H, Pauptit RA, Wallis R, James R, Moore GR, Kleanthous C, Biochem J. 1998 Jul 1;333 ( Pt 1):183-91. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9639578 9639578]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Dennis, C A.]]
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[[Category: Dennis CA]]
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[[Category: James, R.]]
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[[Category: James R]]
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[[Category: Kleanthous, C.]]
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[[Category: Kleanthous C]]
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[[Category: Moore, G R.]]
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[[Category: Moore GR]]
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[[Category: Pauptit, R A.]]
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[[Category: Pauptit RA]]
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[[Category: Wallis, R.]]
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[[Category: Wallis R]]
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[[Category: Bacteriocin]]
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[[Category: Dnase inhibitor]]
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[[Category: E colicin]]
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[[Category: Protein-protein interaction]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 17:51:35 2008''
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Current revision

COLICIN E7 IMMUNITY PROTEIN IM7

PDB ID 1ayi

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