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1b1z

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{{Seed}}
 
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[[Image:1b1z.png|left|200px]]
 
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==STREPTOCOCCAL PYROGENIC EXOTOXIN A1==
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The line below this paragraph, containing "STRUCTURE_1b1z", creates the "Structure Box" on the page.
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<StructureSection load='1b1z' size='340' side='right'caption='[[1b1z]], [[Resolution|resolution]] 2.57&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1b1z]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B1Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1B1Z FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.57&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1b1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b1z OCA], [https://pdbe.org/1b1z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1b1z RCSB], [https://www.ebi.ac.uk/pdbsum/1b1z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1b1z ProSAT]</span></td></tr>
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{{STRUCTURE_1b1z| PDB=1b1z | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SPEA_STRPY SPEA_STRPY] Causative agent of the symptoms associated with scarlet fever, have been associated with streptococcal toxic shock-like disease and may play a role in the early events of rheumatic fever.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b1/1b1z_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1b1z ConSurf].
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<div style="clear:both"></div>
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===STREPTOCOCCAL PYROGENIC EXOTOXIN A1===
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==See Also==
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*[[Exotoxin 3D structures|Exotoxin 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_9878045}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 9878045 is the PubMed ID number.
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-->
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{{ABSTRACT_PUBMED_9878045}}
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==About this Structure==
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1B1Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B1Z OCA].
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==Reference==
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Structural basis for the recognition of superantigen streptococcal pyrogenic exotoxin A (SpeA1) by MHC class II molecules and T-cell receptors., Papageorgiou AC, Collins CM, Gutman DM, Kline JB, O'Brien SM, Tranter HS, Acharya KR, EMBO J. 1999 Jan 4;18(1):9-21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9878045 9878045]
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[[Category: Single protein]]
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[[Category: Streptococcus pyogenes]]
[[Category: Streptococcus pyogenes]]
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[[Category: Acharya, K R.]]
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[[Category: Acharya KR]]
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[[Category: Papageorgiou, A C.]]
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[[Category: Papageorgiou AC]]
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[[Category: Pyrogenic exotoxin]]
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[[Category: Superantigen]]
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[[Category: Zinc binding]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 18:03:12 2008''
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Current revision

STREPTOCOCCAL PYROGENIC EXOTOXIN A1

PDB ID 1b1z

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