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1b62

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{{Seed}}
 
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[[Image:1b62.png|left|200px]]
 
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==MUTL COMPLEXED WITH ADP==
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The line below this paragraph, containing "STRUCTURE_1b62", creates the "Structure Box" on the page.
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<StructureSection load='1b62' size='340' side='right'caption='[[1b62]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1b62]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B62 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1B62 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_1b62| PDB=1b62 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1b62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b62 OCA], [https://pdbe.org/1b62 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1b62 RCSB], [https://www.ebi.ac.uk/pdbsum/1b62 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1b62 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MUTL_ECOLI MUTL_ECOLI] This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of the final effector complex. The ATPase activity of MutL is stimulated by DNA.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/1b62_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1b62 ConSurf].
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<div style="clear:both"></div>
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===MUTL COMPLEXED WITH ADP===
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==See Also==
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*[[DNA mismatch repair protein 3D structures|DNA mismatch repair protein 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_10199405}}, adds the Publication Abstract to the page
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[[Category: Escherichia coli K-12]]
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(as it appears on PubMed at http://www.pubmed.gov), where 10199405 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Wei Y]]
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{{ABSTRACT_PUBMED_10199405}}
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==About this Structure==
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1B62 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B62 OCA].
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==Reference==
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Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair., Ban C, Junop M, Yang W, Cell. 1999 Apr 2;97(1):85-97. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10199405 10199405]
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[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Wei, Y.]]
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[[Category: Atpase]]
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[[Category: Dna mismatch repair]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 18:20:47 2008''
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Current revision

MUTL COMPLEXED WITH ADP

PDB ID 1b62

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