1bc1

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{{Seed}}
 
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[[Image:1bc1.png|left|200px]]
 
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==RECOMBINANT RAT ANNEXIN V, QUADRUPLE MUTANT (T72K, S144K, S228K, S303K)==
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The line below this paragraph, containing "STRUCTURE_1bc1", creates the "Structure Box" on the page.
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<StructureSection load='1bc1' size='340' side='right'caption='[[1bc1]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1bc1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BC1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BC1 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1bc1| PDB=1bc1 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bc1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bc1 OCA], [https://pdbe.org/1bc1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bc1 RCSB], [https://www.ebi.ac.uk/pdbsum/1bc1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bc1 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ANXA5_RAT ANXA5_RAT] This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bc/1bc1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bc1 ConSurf].
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<div style="clear:both"></div>
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===RECOMBINANT RAT ANNEXIN V, QUADRUPLE MUTANT (T72K, S144K, S228K, S303K)===
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==See Also==
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*[[Annexin 3D structures|Annexin 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_9609693}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 9609693 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9609693}}
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==About this Structure==
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1BC1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BC1 OCA].
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==Reference==
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Mutational and crystallographic analyses of interfacial residues in annexin V suggest direct interactions with phospholipid membrane components., Campos B, Mo YD, Mealy TR, Li CW, Swairjo MA, Balch C, Head JF, Retzinger G, Dedman JR, Seaton BA, Biochemistry. 1998 Jun 2;37(22):8004-10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9609693 9609693]
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[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Single protein]]
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[[Category: Head JF]]
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[[Category: Head, J F.]]
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[[Category: Li CW]]
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[[Category: Li, C W.]]
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[[Category: Mo YD]]
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[[Category: Mo, Y D.]]
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[[Category: Seaton BA]]
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[[Category: Seaton, B A.]]
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[[Category: Swairjo MA]]
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[[Category: Swairjo, M A.]]
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[[Category: Calcium binding protein]]
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[[Category: Phospholipid membrane binding protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 18:47:59 2008''
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Current revision

RECOMBINANT RAT ANNEXIN V, QUADRUPLE MUTANT (T72K, S144K, S228K, S303K)

PDB ID 1bc1

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