1bg8

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{{Seed}}
 
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[[Image:1bg8.png|left|200px]]
 
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==HDEA FROM ESCHERICHIA COLI==
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The line below this paragraph, containing "STRUCTURE_1bg8", creates the "Structure Box" on the page.
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<StructureSection load='1bg8' size='340' side='right'caption='[[1bg8]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1bg8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BG8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BG8 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bg8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bg8 OCA], [https://pdbe.org/1bg8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bg8 RCSB], [https://www.ebi.ac.uk/pdbsum/1bg8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bg8 ProSAT]</span></td></tr>
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{{STRUCTURE_1bg8| PDB=1bg8 | SCENE= }}
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</table>
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== Function ==
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===HDEA FROM ESCHERICHIA COLI===
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[https://www.uniprot.org/uniprot/HDEA_ECOLI HDEA_ECOLI] Required for optimal acid stress protection. Exhibits a chaperone-like activity only at pH below 3 by suppressing non-specifically the aggregation of denaturated periplasmic proteins. Important for survival of enteric bacteria in the acidic environment of the host stomach. Also promotes the solubilization at neutral pH of proteins that had aggregated in their presence at acidic pHs. May cooperate with other periplasmic chaperones such as DegP and SurA.<ref>PMID:15911614</ref> <ref>PMID:17085547</ref> <ref>PMID:18359765</ref> <ref>PMID:21892184</ref>
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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1BG8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BG8 OCA].
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</StructureSection>
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==Reference==
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Crystal structure of Escherichia coli HdeA., Yang F, Gustafson KR, Boyd MR, Wlodawer A, Nat Struct Biol. 1998 Sep;5(9):763-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9731767 9731767]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Boyd, M R.]]
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[[Category: Boyd MR]]
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[[Category: Gustafson, K R.]]
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[[Category: Gustafson KR]]
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[[Category: Wlodawer, A.]]
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[[Category: Wlodawer A]]
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[[Category: Yang, F.]]
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[[Category: Yang F]]
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[[Category: Hdea]]
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[[Category: Periplasmic]]
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[[Category: Signal]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 19:05:52 2008''
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Current revision

HDEA FROM ESCHERICHIA COLI

PDB ID 1bg8

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