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1bhs

From Proteopedia

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{{Seed}}
 
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[[Image:1bhs.png|left|200px]]
 
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==HUMAN ESTROGENIC 17BETA-HYDROXYSTEROID DEHYDROGENASE==
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The line below this paragraph, containing "STRUCTURE_1bhs", creates the "Structure Box" on the page.
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<StructureSection load='1bhs' size='340' side='right'caption='[[1bhs]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1bhs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BHS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BHS FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bhs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bhs OCA], [https://pdbe.org/1bhs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bhs RCSB], [https://www.ebi.ac.uk/pdbsum/1bhs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bhs ProSAT]</span></td></tr>
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{{STRUCTURE_1bhs| PDB=1bhs | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DHB1_HUMAN DHB1_HUMAN] Favors the reduction of estrogens and androgens. Also has 20-alpha-HSD activity. Uses preferentially NADH.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bh/1bhs_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bhs ConSurf].
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<div style="clear:both"></div>
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===HUMAN ESTROGENIC 17BETA-HYDROXYSTEROID DEHYDROGENASE===
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==See Also==
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*[[Hydroxysteroid dehydrogenase 3D structures|Hydroxysteroid dehydrogenase 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_7663947}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 7663947 is the PubMed ID number.
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-->
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{{ABSTRACT_PUBMED_7663947}}
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==About this Structure==
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1BHS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BHS OCA].
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==Reference==
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Structure of human estrogenic 17 beta-hydroxysteroid dehydrogenase at 2.20 A resolution., Ghosh D, Pletnev VZ, Zhu DW, Wawrzak Z, Duax WL, Pangborn W, Labrie F, Lin SX, Structure. 1995 May 15;3(5):503-13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7663947 7663947]
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[[Category: Estradiol 17-beta-dehydrogenase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Ghosh, D.]]
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[[Category: Ghosh D]]
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[[Category: Estrogen]]
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[[Category: Human placental 17beta-hsd]]
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[[Category: Human type i 17beta-hsd]]
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[[Category: Oxidoreductase]]
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[[Category: Short-chain dehydrogenase]]
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[[Category: Steroid dehydrogenase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 19:11:22 2008''
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Current revision

HUMAN ESTROGENIC 17BETA-HYDROXYSTEROID DEHYDROGENASE

PDB ID 1bhs

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