1biv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:06, 10 April 2024) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1biv.png|left|200px]]
 
-
<!--
+
==BOVINE IMMUNODEFICIENCY VIRUS TAT-TAR COMPLEX, NMR, 5 STRUCTURES==
-
The line below this paragraph, containing "STRUCTURE_1biv", creates the "Structure Box" on the page.
+
<StructureSection load='1biv' size='340' side='right'caption='[[1biv]]' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1biv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bovine_immunodeficiency_virus Bovine immunodeficiency virus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BIV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BIV FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1biv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1biv OCA], [https://pdbe.org/1biv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1biv RCSB], [https://www.ebi.ac.uk/pdbsum/1biv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1biv ProSAT]</span></td></tr>
-
{{STRUCTURE_1biv| PDB=1biv | SCENE= }}
+
</table>
-
 
+
== Function ==
-
===BOVINE IMMUNODEFICIENCY VIRUS TAT-TAR COMPLEX, NMR, 5 STRUCTURES===
+
[https://www.uniprot.org/uniprot/TAT_BIV29 TAT_BIV29] Nuclear transcriptional activator of viral gene expression, that is essential for viral transcription from the LTR promoter and replication. Acts as a sequence-specific molecular adapter, directing components of the cellular transcription machinery to the viral RNA to promote processive transcription elongation by the RNA polymerase II (RNA pol II) complex, thereby increasing the level of full-length transcripts. Tat binds to a hairpin structure at the 5'-end of all nascent viral mRNAs referred to as the transactivation responsive RNA element (TAR RNA) in a CCNT1-independent mode. Tat then recruits the CCNT1/cyclin-T1 component of the P-TEFb complex (CDK9 and CCNT1), which promotes RNA chain elongation. The CDK9 component of P-TEFb hyperphosphorylates the C-terminus of RNA Pol II that becomes stabilized and much more processive (Probable).<ref>PMID:10846086</ref>
-
 
+
== References ==
-
 
+
<references/>
-
<!--
+
__TOC__
-
The line below this paragraph, {{ABSTRACT_PUBMED_8807816}}, adds the Publication Abstract to the page
+
</StructureSection>
-
(as it appears on PubMed at http://www.pubmed.gov), where 8807816 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_8807816}}
+
-
 
+
-
==About this Structure==
+
-
1BIV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bovine_immunodeficiency_virus Bovine immunodeficiency virus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BIV OCA].
+
-
 
+
-
==Reference==
+
-
Molecular recognition in the bovine immunodeficiency virus Tat peptide-TAR RNA complex., Ye X, Kumar RA, Patel DJ, Chem Biol. 1995 Dec;2(12):827-40. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8807816 8807816]
+
[[Category: Bovine immunodeficiency virus]]
[[Category: Bovine immunodeficiency virus]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Kumar, R A.]]
+
[[Category: Synthetic construct]]
-
[[Category: Patel, D J.]]
+
[[Category: Kumar RA]]
-
[[Category: Ye, X.]]
+
[[Category: Patel DJ]]
-
[[Category: Arg-gua interaction]]
+
[[Category: Ye X]]
-
[[Category: Bovine immunodeficiency virus]]
+
-
[[Category: Glycine and isoleucine packing]]
+
-
[[Category: Peptide rna recognition]]
+
-
[[Category: Rna bending]]
+
-
[[Category: Tat-tar]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 19:14:07 2008''
+

Current revision

BOVINE IMMUNODEFICIENCY VIRUS TAT-TAR COMPLEX, NMR, 5 STRUCTURES

PDB ID 1biv

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1biv"
Personal tools