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1biy

From Proteopedia

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{{Seed}}
 
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[[Image:1biy.png|left|200px]]
 
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==STRUCTURE OF DIFERRIC BUFFALO LACTOFERRIN==
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The line below this paragraph, containing "STRUCTURE_1biy", creates the "Structure Box" on the page.
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<StructureSection load='1biy' size='340' side='right'caption='[[1biy]], [[Resolution|resolution]] 3.37&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1biy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bubalus_bubalis Bubalus bubalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BIY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BIY FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.37&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
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{{STRUCTURE_1biy| PDB=1biy | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1biy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1biy OCA], [https://pdbe.org/1biy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1biy RCSB], [https://www.ebi.ac.uk/pdbsum/1biy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1biy ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRFL_BUBBU TRFL_BUBBU] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bi/1biy_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1biy ConSurf].
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<div style="clear:both"></div>
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===STRUCTURE OF DIFERRIC BUFFALO LACTOFERRIN===
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==See Also==
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*[[Lactoferrin|Lactoferrin]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_10818344}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 10818344 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10818344}}
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==About this Structure==
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1BIY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bubalus_bubalis Bubalus bubalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BIY OCA].
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==Reference==
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Structure of buffalo lactoferrin at 3.3 A resolution at 277 K., Karthikeyan S, Yadav S, Paramasivam M, Srinivasan A, Singh TP, Acta Crystallogr D Biol Crystallogr. 2000 Jun;56(Pt 6):684-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10818344 10818344]
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[[Category: Bubalus bubalis]]
[[Category: Bubalus bubalis]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Karthikeyan, S.]]
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[[Category: Karthikeyan S]]
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[[Category: Singh, T P.]]
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[[Category: Singh TP]]
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[[Category: Yadav, S.]]
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[[Category: Yadav S]]
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[[Category: Antibacterial]]
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[[Category: Iron binding protein]]
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[[Category: Lactoferrin]]
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[[Category: Structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 19:14:18 2008''
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Current revision

STRUCTURE OF DIFERRIC BUFFALO LACTOFERRIN

PDB ID 1biy

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