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1bmp

From Proteopedia

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{{Seed}}
 
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[[Image:1bmp.png|left|200px]]
 
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==BONE MORPHOGENETIC PROTEIN-7==
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The line below this paragraph, containing "STRUCTURE_1bmp", creates the "Structure Box" on the page.
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<StructureSection load='1bmp' size='340' side='right'caption='[[1bmp]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1bmp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BMP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BMP FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bmp OCA], [https://pdbe.org/1bmp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bmp RCSB], [https://www.ebi.ac.uk/pdbsum/1bmp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bmp ProSAT]</span></td></tr>
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{{STRUCTURE_1bmp| PDB=1bmp | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BMP7_HUMAN BMP7_HUMAN] Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bm/1bmp_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bmp ConSurf].
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<div style="clear:both"></div>
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===BONE MORPHOGENETIC PROTEIN-7===
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==See Also==
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*[[Bone morphogenetic protein 3D structures|Bone morphogenetic protein 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_8570652}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 8570652 is the PubMed ID number.
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-->
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{{ABSTRACT_PUBMED_8570652}}
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==About this Structure==
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1BMP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BMP OCA].
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==Reference==
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Three-dimensional structure of recombinant human osteogenic protein 1: structural paradigm for the transforming growth factor beta superfamily., Griffith DL, Keck PC, Sampath TK, Rueger DC, Carlson WD, Proc Natl Acad Sci U S A. 1996 Jan 23;93(2):878-83. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8570652 8570652]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Griffith, D L.]]
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[[Category: Griffith DL]]
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[[Category: Scott, D L.]]
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[[Category: Scott DL]]
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[[Category: Bone]]
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[[Category: Cartilage]]
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[[Category: Cytokine]]
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[[Category: Glycoprotein]]
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[[Category: Morphogen]]
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[[Category: Transforming growth factor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 19:23:35 2008''
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Current revision

BONE MORPHOGENETIC PROTEIN-7

PDB ID 1bmp

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