1bn0
From Proteopedia
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- | {{Seed}} | ||
- | [[Image:1bn0.png|left|200px]] | ||
- | < | + | ==SL3 HAIRPIN FROM THE PACKAGING SIGNAL OF HIV-1, NMR, 11 STRUCTURES== |
- | + | <StructureSection load='1bn0' size='340' side='right'caption='[[1bn0]]' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1bn0]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BN0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BN0 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
- | - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bn0 OCA], [https://pdbe.org/1bn0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bn0 RCSB], [https://www.ebi.ac.uk/pdbsum/1bn0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bn0 ProSAT]</span></td></tr> |
- | + | </table> | |
+ | <div style="background-color:#fffaf0;"> | ||
+ | == Publication Abstract from PubMed == | ||
+ | An NMR-based structure is presented for a 20 mer hairpin model of the SL3 stem-loop from the HIV-1 packaging signal. The stem has an A-family structure. However, the GGAG tetraloop appears to be flexible with the second (G10) and fourth (G12) bases extruded from the normal stacking arrangement. The A-base (A11) occupies a cavity large enough for it to jump rapidly between stacking upon G9 (in the loop) and G13 (from the base-pair adjacent to the loop). The H-bonding loci of G10, A11, and G12 are unoccupied in the free RNA structure. The loop should be easily adaptable to binding by the HIV-1 nucleocapsid protein or loop receptors. | ||
- | + | Three-dimensional folding of an RNA hairpin required for packaging HIV-1.,Pappalardo L, Kerwood DJ, Pelczer I, Borer PN J Mol Biol. 1998 Oct 2;282(4):801-18. PMID:9743628<ref>PMID:9743628</ref> | |
- | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
- | + | </div> | |
- | + | <div class="pdbe-citations 1bn0" style="background-color:#fffaf0;"></div> | |
- | + | == References == | |
- | --> | + | <references/> |
- | + | __TOC__ | |
- | + | </StructureSection> | |
- | == | + | [[Category: Large Structures]] |
- | + | [[Category: Borer PN]] | |
- | + | [[Category: Kerwood DJ]] | |
- | + | [[Category: Pappalardo L]] | |
- | + | [[Category: Pelczer I]] | |
- | [[Category: Borer | + | |
- | [[Category: Kerwood | + | |
- | [[Category: Pappalardo | + | |
- | [[Category: Pelczer | + | |
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Current revision
SL3 HAIRPIN FROM THE PACKAGING SIGNAL OF HIV-1, NMR, 11 STRUCTURES
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