1brk

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:38, 7 February 2024) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1brk.png|left|200px]]
 
-
<!--
+
==BARNASE MUTANT WITH ILE 96 REPLACED BY ALA==
-
The line below this paragraph, containing "STRUCTURE_1brk", creates the "Structure Box" on the page.
+
<StructureSection load='1brk' size='340' side='right'caption='[[1brk]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1brk]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_amyloliquefaciens Bacillus amyloliquefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BRK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BRK FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
{{STRUCTURE_1brk| PDB=1brk | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1brk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1brk OCA], [https://pdbe.org/1brk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1brk RCSB], [https://www.ebi.ac.uk/pdbsum/1brk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1brk ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/RNBR_BACAM RNBR_BACAM] Hydrolyzes phosphodiester bonds in RNA, poly- and oligoribonucleotides resulting in 3'-nucleoside monophosphates via 2',3'-cyclophosphate intermediates.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/1brk_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1brk ConSurf].
 +
<div style="clear:both"></div>
-
===BARNASE MUTANT WITH ILE 96 REPLACED BY ALA===
+
==See Also==
-
 
+
*[[Barnase 3D structures|Barnase 3D structures]]
-
 
+
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
-
<!--
+
__TOC__
-
The line below this paragraph, {{ABSTRACT_PUBMED_8605178}}, adds the Publication Abstract to the page
+
</StructureSection>
-
(as it appears on PubMed at http://www.pubmed.gov), where 8605178 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_8605178}}
+
-
 
+
-
==About this Structure==
+
-
1BRK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_amyloliquefaciens Bacillus amyloliquefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BRK OCA].
+
-
 
+
-
==Reference==
+
-
Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities., Buckle AM, Cramer P, Fersht AR, Biochemistry. 1996 Apr 9;35(14):4298-305. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8605178 8605178]
+
[[Category: Bacillus amyloliquefaciens]]
[[Category: Bacillus amyloliquefaciens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Buckle, A.]]
+
[[Category: Buckle A]]
-
[[Category: Cramer, P C.]]
+
[[Category: Cramer PC]]
-
[[Category: Fersht, A.]]
+
[[Category: Fersht A]]
-
[[Category: Alpha/beta protein]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 19:36:42 2008''
+

Current revision

BARNASE MUTANT WITH ILE 96 REPLACED BY ALA

PDB ID 1brk

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1brk"
Personal tools