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1btn

From Proteopedia

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{{Seed}}
 
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[[Image:1btn.png|left|200px]]
 
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<!--
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==STRUCTURE OF THE BINDING SITE FOR INOSITOL PHOSPHATES IN A PH DOMAIN==
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The line below this paragraph, containing "STRUCTURE_1btn", creates the "Structure Box" on the page.
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<StructureSection load='1btn' size='340' side='right'caption='[[1btn]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1btn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BTN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BTN FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=I3P:D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE'>I3P</scene></td></tr>
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{{STRUCTURE_1btn| PDB=1btn | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1btn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1btn OCA], [https://pdbe.org/1btn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1btn RCSB], [https://www.ebi.ac.uk/pdbsum/1btn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1btn ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SPTB2_MOUSE SPTB2_MOUSE] Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bt/1btn_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1btn ConSurf].
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<div style="clear:both"></div>
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===STRUCTURE OF THE BINDING SITE FOR INOSITOL PHOSPHATES IN A PH DOMAIN===
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==See Also==
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*[[Spectrin 3D structures|Spectrin 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_7588597}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 7588597 is the PubMed ID number.
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-->
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{{ABSTRACT_PUBMED_7588597}}
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==About this Structure==
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1BTN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BTN OCA].
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==Reference==
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Structure of the binding site for inositol phosphates in a PH domain., Hyvonen M, Macias MJ, Nilges M, Oschkinat H, Saraste M, Wilmanns M, EMBO J. 1995 Oct 2;14(19):4676-85. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7588597 7588597]
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Single protein]]
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[[Category: Hyvoenen M]]
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[[Category: Hyvoenen, M.]]
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[[Category: Saraste M]]
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[[Category: Saraste, M.]]
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[[Category: Wilmanns M]]
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[[Category: Wilmanns, M.]]
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[[Category: Signal transduction protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 19:42:17 2008''
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Current revision

STRUCTURE OF THE BINDING SITE FOR INOSITOL PHOSPHATES IN A PH DOMAIN

PDB ID 1btn

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