1bwr

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{{Seed}}
 
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[[Image:1bwr.png|left|200px]]
 
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==PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE==
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The line below this paragraph, containing "STRUCTURE_1bwr", creates the "Structure Box" on the page.
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<StructureSection load='1bwr' size='340' side='right'caption='[[1bwr]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1bwr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BWR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BWR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bwr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bwr OCA], [https://pdbe.org/1bwr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bwr RCSB], [https://www.ebi.ac.uk/pdbsum/1bwr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bwr ProSAT]</span></td></tr>
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{{STRUCTURE_1bwr| PDB=1bwr | SCENE= }}
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</table>
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== Function ==
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===PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE===
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[https://www.uniprot.org/uniprot/PA1B3_BOVIN PA1B3_BOVIN] Inactivates paf by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Plays an important role during the development of brain.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_10469831}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 10469831 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bw/1bwr_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_10469831}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bwr ConSurf].
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1BWR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BWR OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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Probing the substrate specificity of the intracellular brain platelet-activating factor acetylhydrolase., Ho YS, Sheffield PJ, Masuyama J, Arai H, Li J, Aoki J, Inoue K, Derewenda U, Derewenda ZS, Protein Eng. 1999 Aug;12(8):693-700. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10469831 10469831]
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[[Category: 1-alkyl-2-acetylglycerophosphocholine esterase]]
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Aoki, J.]]
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[[Category: Aoki J]]
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[[Category: Arai, H.]]
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[[Category: Arai H]]
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[[Category: Derewenda, U.]]
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[[Category: Derewenda U]]
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[[Category: Derewenda, Z.]]
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[[Category: Derewenda Z]]
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[[Category: Ho, Y S.]]
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[[Category: Ho YS]]
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[[Category: Inoue, K.]]
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[[Category: Inoue K]]
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[[Category: Li, J.]]
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[[Category: Li J]]
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[[Category: Masuyama, J.]]
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[[Category: Masuyama J]]
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[[Category: Sheffield, P J.]]
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[[Category: Sheffield PJ]]
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[[Category: Acetylhydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 19:50:18 2008''
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Current revision

PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE

PDB ID 1bwr

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