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1c5a

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{{Seed}}
 
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[[Image:1c5a.png|left|200px]]
 
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==THREE-DIMENSIONAL STRUCTURE OF PORCINE C5ADES*ARG FROM 1H NUCLEAR MAGNETIC RESONANCE DATA==
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The line below this paragraph, containing "STRUCTURE_1c5a", creates the "Structure Box" on the page.
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<StructureSection load='1c5a' size='340' side='right'caption='[[1c5a]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1c5a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa_domesticus Sus scrofa domesticus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C5A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C5A FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c5a OCA], [https://pdbe.org/1c5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c5a RCSB], [https://www.ebi.ac.uk/pdbsum/1c5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c5a ProSAT]</span></td></tr>
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{{STRUCTURE_1c5a| PDB=1c5a | SCENE= }}
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</table>
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== Function ==
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===THREE-DIMENSIONAL STRUCTURE OF PORCINE C5ADES*ARG FROM 1H NUCLEAR MAGNETIC RESONANCE DATA===
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[https://www.uniprot.org/uniprot/CO5_PIG CO5_PIG] Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C5a also stimulates the locomotion of polymorphonuclear leukocytes (chemokinesis) and direct their migration toward sites of inflammation (chemotaxis).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_2337573}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 2337573 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c5/1c5a_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_2337573}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1c5a ConSurf].
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1C5A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa_domestica Sus scrofa domestica]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C5A OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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Three-dimensional structure of porcine C5adesArg from 1H nuclear magnetic resonance data., Williamson MP, Madison VS, Biochemistry. 1990 Mar 27;29(12):2895-905. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2337573 2337573]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Sus scrofa domesticus]]
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[[Category: Sus scrofa domestica]]
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[[Category: Madison VS]]
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[[Category: Madison, V S.]]
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[[Category: Williamson MP]]
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[[Category: Williamson, M P.]]
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[[Category: Complement factor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 20:13:49 2008''
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Current revision

THREE-DIMENSIONAL STRUCTURE OF PORCINE C5ADES*ARG FROM 1H NUCLEAR MAGNETIC RESONANCE DATA

PDB ID 1c5a

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