1c9b

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{{Seed}}
 
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[[Image:1c9b.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF A HUMAN TBP CORE DOMAIN-HUMAN TFIIB CORE DOMAIN COMPLEX BOUND TO AN EXTENDED, MODIFIED ADENOVIRAL MAJOR LATE PROMOTER (ADMLP)==
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The line below this paragraph, containing "STRUCTURE_1c9b", creates the "Structure Box" on the page.
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<StructureSection load='1c9b' size='340' side='right'caption='[[1c9b]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1c9b]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C9B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C9B FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c9b OCA], [https://pdbe.org/1c9b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c9b RCSB], [https://www.ebi.ac.uk/pdbsum/1c9b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c9b ProSAT]</span></td></tr>
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{{STRUCTURE_1c9b| PDB=1c9b | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TF2B_HUMAN TF2B_HUMAN] General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c9/1c9b_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1c9b ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF A HUMAN TBP CORE DOMAIN-HUMAN TFIIB CORE DOMAIN COMPLEX BOUND TO AN EXTENDED, MODIFIED ADENOVIRAL MAJOR LATE PROMOTER (ADMLP)===
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==See Also==
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*[[TATA-binding protein 3D structures|TATA-binding protein 3D structures]]
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*[[Transcription initiation factors 3D structures|Transcription initiation factors 3D structures]]
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 10619841 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10619841}}
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==About this Structure==
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1C9B is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C9B OCA].
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==Reference==
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Structural basis of preinitiation complex assembly on human pol II promoters., Tsai FT, Sigler PB, EMBO J. 2000 Jan 4;19(1):25-36. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10619841 10619841]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein complex]]
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[[Category: Large Structures]]
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[[Category: Sigler, P B.]]
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[[Category: Sigler PB]]
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[[Category: Tsai, F T.F.]]
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[[Category: Tsai FTF]]
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[[Category: Cyclin-like fold]]
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[[Category: Helix-turn-helix]]
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[[Category: Protein-dna complex]]
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[[Category: Tata-box]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 20:24:02 2008''
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Current revision

CRYSTAL STRUCTURE OF A HUMAN TBP CORE DOMAIN-HUMAN TFIIB CORE DOMAIN COMPLEX BOUND TO AN EXTENDED, MODIFIED ADENOVIRAL MAJOR LATE PROMOTER (ADMLP)

PDB ID 1c9b

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