1cdh

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{{Seed}}
 
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[[Image:1cdh.png|left|200px]]
 
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==STRUCTURES OF AN HIV AND MHC BINDING FRAGMENT FROM HUMAN CD4 AS REFINED IN TWO CRYSTAL LATTICES==
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The line below this paragraph, containing "STRUCTURE_1cdh", creates the "Structure Box" on the page.
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<StructureSection load='1cdh' size='340' side='right'caption='[[1cdh]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1cdh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1cd4 1cd4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CDH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CDH FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cdh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cdh OCA], [https://pdbe.org/1cdh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cdh RCSB], [https://www.ebi.ac.uk/pdbsum/1cdh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cdh ProSAT]</span></td></tr>
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{{STRUCTURE_1cdh| PDB=1cdh | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CD4_HUMAN CD4_HUMAN] Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cd/1cdh_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cdh ConSurf].
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<div style="clear:both"></div>
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===STRUCTURES OF AN HIV AND MHC BINDING FRAGMENT FROM HUMAN CD4 AS REFINED IN TWO CRYSTAL LATTICES===
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==See Also==
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*[[CD4 3D structures|CD4 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_8075984}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 8075984 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8075984}}
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==About this Structure==
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1CDH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1cd4 1cd4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CDH OCA].
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==Reference==
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Structures of an HIV and MHC binding fragment from human CD4 as refined in two crystal lattices., Ryu SE, Truneh A, Sweet RW, Hendrickson WA, Structure. 1994 Jan 15;2(1):59-74. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8075984 8075984]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Hendrickson, W A.]]
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[[Category: Hendrickson WA]]
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[[Category: Ryu, S E.]]
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[[Category: Ryu SE]]
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[[Category: Sweet, R W.]]
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[[Category: Sweet RW]]
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[[Category: Truneh, A.]]
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[[Category: Truneh A]]
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[[Category: T-cell surface glycoprotein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 20:35:26 2008''
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Current revision

STRUCTURES OF AN HIV AND MHC BINDING FRAGMENT FROM HUMAN CD4 AS REFINED IN TWO CRYSTAL LATTICES

PDB ID 1cdh

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