This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1cdj

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:39, 13 March 2024) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1cdj.png|left|200px]]
 
-
<!--
+
==STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4==
-
The line below this paragraph, containing "STRUCTURE_1cdj", creates the "Structure Box" on the page.
+
<StructureSection load='1cdj' size='340' side='right'caption='[[1cdj]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1cdj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CDJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CDJ FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cdj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cdj OCA], [https://pdbe.org/1cdj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cdj RCSB], [https://www.ebi.ac.uk/pdbsum/1cdj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cdj ProSAT]</span></td></tr>
-
{{STRUCTURE_1cdj| PDB=1cdj | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CD4_HUMAN CD4_HUMAN] Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cd/1cdj_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cdj ConSurf].
 +
<div style="clear:both"></div>
-
===STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4===
+
==See Also==
-
 
+
*[[CD4 3D structures|CD4 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_8986758}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 8986758 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_8986758}}
+
-
 
+
-
==About this Structure==
+
-
1CDJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CDJ OCA].
+
-
 
+
-
==Reference==
+
-
Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding., Wu H, Myszka DG, Tendian SW, Brouillette CG, Sweet RW, Chaiken IM, Hendrickson WA, Proc Natl Acad Sci U S A. 1996 Dec 24;93(26):15030-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8986758 8986758]
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Brouillette, C G.]]
+
[[Category: Brouillette CG]]
-
[[Category: Chaiken, I M.]]
+
[[Category: Chaiken IM]]
-
[[Category: Hendrickson, W A.]]
+
[[Category: Hendrickson WA]]
-
[[Category: Myszka, D.]]
+
[[Category: Myszka D]]
-
[[Category: Sweet, R W.]]
+
[[Category: Sweet RW]]
-
[[Category: Tendian, S W.]]
+
[[Category: Tendian SW]]
-
[[Category: Wu, H.]]
+
[[Category: Wu H]]
-
[[Category: Glycoprotein]]
+
-
[[Category: Immunoglobulin fold]]
+
-
[[Category: Lipoprotein]]
+
-
[[Category: Mhc]]
+
-
[[Category: T-cell]]
+
-
[[Category: Transmembrane]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 20:35:34 2008''
+

Current revision

STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4

PDB ID 1cdj

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1cdj"
Personal tools