1coo

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{{Seed}}
 
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[[Image:1coo.png|left|200px]]
 
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==THE COOH-TERMINAL DOMAIN OF RNA POLYMERASE ALPHA SUBUNIT==
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The line below this paragraph, containing "STRUCTURE_1coo", creates the "Structure Box" on the page.
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<StructureSection load='1coo' size='340' side='right'caption='[[1coo]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1coo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1COO FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1coo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1coo OCA], [https://pdbe.org/1coo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1coo RCSB], [https://www.ebi.ac.uk/pdbsum/1coo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1coo ProSAT]</span></td></tr>
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{{STRUCTURE_1coo| PDB=1coo | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/co/1coo_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1coo ConSurf].
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<div style="clear:both"></div>
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===THE COOH-TERMINAL DOMAIN OF RNA POLYMERASE ALPHA SUBUNIT===
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==See Also==
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_7491496}}, adds the Publication Abstract to the page
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[[Category: Escherichia coli K-12]]
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(as it appears on PubMed at http://www.pubmed.gov), where 7491496 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Fujita N]]
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{{ABSTRACT_PUBMED_7491496}}
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[[Category: Ishihama A]]
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[[Category: Jeon YH]]
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==About this Structure==
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[[Category: Kyogoku Y]]
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1COO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA].
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[[Category: Negishi T]]
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[[Category: Shirakawa M]]
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==Reference==
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[[Category: Yamazaki T]]
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Solution structure of the activator contact domain of the RNA polymerase alpha subunit., Jeon YH, Negishi T, Shirakawa M, Yamazaki T, Fujita N, Ishihama A, Kyogoku Y, Science. 1995 Dec 1;270(5241):1495-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7491496 7491496]
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[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Fujita, N.]]
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[[Category: Ishihama, A.]]
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[[Category: Jeon, Y H.]]
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[[Category: Kyogoku, Y.]]
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[[Category: Negishi, T.]]
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[[Category: Shirakawa, M.]]
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[[Category: Yamazaki, T.]]
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[[Category: Transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 21:01:52 2008''
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Current revision

THE COOH-TERMINAL DOMAIN OF RNA POLYMERASE ALPHA SUBUNIT

PDB ID 1coo

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