This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1cps

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:41, 13 March 2024) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1cps.png|left|200px]]
 
-
<!--
+
==STRUCTURAL COMPARISON OF SULFODIIMINE AND SULFONAMIDE INHIBITORS IN THEIR COMPLEXES WITH ZINC ENZYMES==
-
The line below this paragraph, containing "STRUCTURE_1cps", creates the "Structure Box" on the page.
+
<StructureSection load='1cps' size='340' side='right'caption='[[1cps]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1cps]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CPS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CPS FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CPM:S-(2-CARBOXY-3-PHENYLPROPYL)THIODIIMINE-S-METHANE'>CPM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
{{STRUCTURE_1cps| PDB=1cps | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cps OCA], [https://pdbe.org/1cps PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cps RCSB], [https://www.ebi.ac.uk/pdbsum/1cps PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cps ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CBPA1_BOVIN CBPA1_BOVIN] Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro (By similarity).
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cp/1cps_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cps ConSurf].
 +
<div style="clear:both"></div>
-
===STRUCTURAL COMPARISON OF SULFODIIMINE AND SULFONAMIDE INHIBITORS IN THEIR COMPLEXES WITH ZINC ENZYMES===
+
==See Also==
-
 
+
*[[Carboxypeptidase 3D structures|Carboxypeptidase 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_1527041}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 1527041 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_1527041}}
+
-
 
+
-
==About this Structure==
+
-
1CPS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CPS OCA].
+
-
 
+
-
==Reference==
+
-
Structural comparison of sulfodiimine and sulfonamide inhibitors in their complexes with zinc enzymes., Cappalonga AM, Alexander RS, Christianson DW, J Biol Chem. 1992 Sep 25;267(27):19192-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1527041 1527041]
+
[[Category: Bos taurus]]
[[Category: Bos taurus]]
-
[[Category: Carboxypeptidase A]]
+
[[Category: Large Structures]]
-
[[Category: Single protein]]
+
[[Category: Alexander RS]]
-
[[Category: Alexander, R S.]]
+
[[Category: Cappalonga AM]]
-
[[Category: Cappalonga, A M.]]
+
[[Category: Christianson DW]]
-
[[Category: Christianson, D W.]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 21:04:13 2008''
+

Current revision

STRUCTURAL COMPARISON OF SULFODIIMINE AND SULFONAMIDE INHIBITORS IN THEIR COMPLEXES WITH ZINC ENZYMES

PDB ID 1cps

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1cps"
Personal tools