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1cr5

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{{Seed}}
 
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[[Image:1cr5.png|left|200px]]
 
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==N-TERMINAL DOMAIN OF SEC18P==
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The line below this paragraph, containing "STRUCTURE_1cr5", creates the "Structure Box" on the page.
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<StructureSection load='1cr5' size='340' side='right'caption='[[1cr5]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1cr5]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CR5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CR5 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NEN:1-ETHYL-PYRROLIDINE-2,5-DIONE'>NEN</scene></td></tr>
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{{STRUCTURE_1cr5| PDB=1cr5 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cr5 OCA], [https://pdbe.org/1cr5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cr5 RCSB], [https://www.ebi.ac.uk/pdbsum/1cr5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cr5 ProSAT]</span></td></tr>
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</table>
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===N-TERMINAL DOMAIN OF SEC18P===
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== Function ==
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[https://www.uniprot.org/uniprot/SEC18_YEAST SEC18_YEAST] Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_10611286}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 10611286 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cr/1cr5_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_10611286}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1CR5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CR5 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cr5 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Crystal structure of the Sec18p N-terminal domain., Babor SM, Fass D, Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14759-64. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10611286 10611286]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Single protein]]
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[[Category: Babor SM]]
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[[Category: Babor, S M.]]
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[[Category: Fass D]]
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[[Category: Fass, D.]]
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[[Category: Double-psi beta barrel]]
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[[Category: Vesicle fusion]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 21:11:52 2008''
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Current revision

N-TERMINAL DOMAIN OF SEC18P

PDB ID 1cr5

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OCA

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